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Symbol
Name
ID
Pkn1
protein kinase N1
MGI:108022
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
decreased activation-induced B cell apoptosis
increased B cell proliferation
abnormal somatic hypermutation frequency
decreased eosinophil cell number
decreased neutrophil cell number
increased germinal center B cell number
decreased lymphocyte cell number
decreased large unstained cell number
decreased monocyte cell number
decreased leukocyte cell number
increased spleen germinal center size
increased splenocyte number
abnormal germinal center B cell physiology
increased IgG1 level
increased IgG2a level
increased IgG2b level
increased IgM level
increased anti-double stranded DNA antibody level
glomerulonephritis
Availability Mouse Genotype
Pkn1tm1b(KOMP)Wtsi/Pkn1tm1b(KOMP)Wtsi
Pkn1tm1Kik/Pkn1tm1Kik *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory