Symbol
Name
ID

Tfam
transcription factor A, mitochondrial
MGI:107810

Phenotype annotations related to behavior/neurological

Darker colors indicate more annotations

Human Phenotypes

Depression

Emotional lability

Atypical behavior

Apathy

Lethargy

Reduced social reciprocity

Personality changes

Impulsivity

Agitation

Restless legs

Fatigue

Pain

Disease(s) Associated with TFAM

amyotrophic lateral sclerosis

Huntington's disease

mitochondrial DNA depletion syndrome 15

Parkinson's disease

Mouse Phenotypes		decreased exploration in new environment	tremors	abnormal limb posture	decreased locomotor activity	bradykinesia
Availability	Mouse Genotype	decreased exploration in new environment	tremors	abnormal limb posture	decreased locomotor activity	bradykinesia
	Tfam^tm1Lrsn/Tfam^tm1Lrsn Tg(Ckmm-cre)1Lrsn/0 (conditional)
	Myl1^tm1(cre)Sjb/Myl1⁺ Tfam^tm1Lrsn/Tfam^tm1Lrsn (conditional)
	Slc6a3^tm1(cre)Lrsn/Slc6a3⁺ Tfam^tm1Lrsn/Tfam^tm1Lrsn (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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