|
Symbol Name ID |
Capn3
calpain 3 MGI:107437 |
| * | Aspects of the system are reported to show a normal phenotype. |
| ! | Indicates phenotype varies with strain background. |
| Darker colors indicate more annotations |
| Human Phenotypes | Facial palsy |
Congenital finger flexion contractures |
Ankle flexion contracture |
Calf muscle hypertrophy |
Scapular muscle atrophy |
Scapular winging |
Lower limb muscle weakness |
Limb-girdle muscular dystrophy |
Pelvic girdle amyotrophy |
Elbow flexion contracture |
Wrist flexion contracture |
Myositis |
Flexion contracture |
Hamstring contractures |
Difficulty climbing stairs |
Difficulty walking |
Muscle weakness |
Generalized muscle weakness |
Proximal muscle weakness |
Myotonia |
Central core regions in muscle fibers |
Pectoralis amyotrophy |
Proximal amyotrophy |
Muscle eosinophilia |
Muscular dystrophy |
Myopathy |
| Disease(s) Associated with CAPN3 | ||||||||||||||||||||||||||
| autosomal recessive limb-girdle muscular dystrophy type 2A | ||||||||||||||||||||||||||
| muscular dystrophy |
| Mouse Phenotypes | muscle phenotype |
abnormal gastrocnemius morphology |
abnormal soleus morphology |
abnormal tibialis anterior morphology |
abnormal muscle morphology |
abnormal sarcolemma morphology |
abnormal A band morphology |
abnormal skeletal muscle fiber morphology |
decreased skeletal muscle fiber diameter |
centrally nucleated skeletal muscle fibers |
abnormal diaphragm morphology |
decreased skeletal muscle mass |
skeletal muscle degeneration |
dystrophic muscle |
|
| Availability | Mouse Genotype | ||||||||||||||
| Capn3Gt(OST141731)Lex/Capn3Gt(OST141731)Lex | |||||||||||||||
| Capn3tm1.1Hiso/Capn3tm1.1Hiso | |||||||||||||||
| Capn3tm1Jsb/Capn3tm1Jsb | ! | ||||||||||||||
| Tg(ACTA1-Capn3)7.2Spc/0 | * | ||||||||||||||
| Tg(ACTA1-Capn3*)10.3Spc/0 | |||||||||||||||
| Tg(ACTA1-Capn3*)27.10Spc/0 | |||||||||||||||
| Tg(ACTA1-Capn3*)37.3Spc/0 | |||||||||||||||
| Tg(ACTA1-Capn3*)37.9Spc/0 | |||||||||||||||
| Tg(ACTA1-Capn3*)39.1Spc/0 | |||||||||||||||
| Tg(ACTA1-Capn3*)41.1Spc/0 | |||||||||||||||
| Tg(ACTA1-Capn3*)42Spc/0 | |||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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