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Symbol
Name
ID
Hif1a
hypoxia inducible factor 1, alpha subunit
MGI:106918
Phenotype annotations related to embryo
Darker colors indicate more annotations

Mouse Phenotypes
absent pharyngeal arch arteries
pharyngeal arch artery hypoplasia
disorganized yolk sac vascular plexus
increased embryonic tissue cell apoptosis
abnormal neural crest cell migration
abnormal pharyngeal arch morphology
absent second pharyngeal arch
small second pharyngeal arch
absent third pharyngeal arch
embryonic growth arrest
embryonic growth retardation
decreased embryo size
abnormal head mesenchyme morphology
abnormal neural fold formation
open neural tube
abnormal somite development
incomplete somite formation
abnormal vitelline vascular remodeling
Availability Mouse Genotype
Hif1atm1Jhu/Hif1atm1Jhu
Hif1atm1Pec/Hif1atm1Pec
Hif1atm1Rsjo/Hif1atm1Rsjo
Hif1atm2Rsjo/Hif1atm2Rsjo
Hif1atm3Rsjo/Hif1atm3Rsjo
Tg(Col2a1-cre)1Rsjo/?  (conditional)
Hif1atm1Rsjo/Hif1atm3Rsjo
Tg(Col2a1-cre)1Rsjo/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory