Symbol
Name
ID

Zic3
zinc finger protein of the cerebellum 3
MGI:106676

Phenotype annotations related to craniofacial

Darker colors indicate more annotations

Human Phenotypes	Microcephaly
Disease(s) Associated with ZIC3	Microcephaly
visceral heterotaxy

Mouse Phenotypes

increased cranium width

abnormal neurocranium morphology

abnormal interfrontal bone morphology

abnormal hyoid bone morphology

absent hyoid bone greater horns

abnormal jaw morphology

malocclusion

abnormal mandible morphology

mandibular coronoid process hypoplasia

premaxilla hypoplasia

maxilla hypoplasia

abnormal zygomatic bone morphology

cranioschisis

hemifacial hypoplasia

cleft palate

abnormal ear position

lowered ear position

Availability

Mouse Genotype

Zic3^Bn/Zic3^Bn

Zic3^tm1Bca/Zic3^tm1Bca

Zic3^tm1Jwb/Zic3^tm1Jwb

Zic3^tm1Bca/Y

Zic3^tm1Jwb/Y

Zic3^tm2.1Jwb/Y
Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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