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Symbol
Name
ID
Zic3
zinc finger protein of the cerebellum 3
MGI:106676
Phenotype annotations related to craniofacial
Darker colors indicate more annotations
Human Phenotypes
Hypertelorism
Disease(s) Associated with ZIC3
visceral heterotaxy

Mouse Phenotypes
increased cranium width
abnormal neurocranium morphology
abnormal interfrontal bone morphology
abnormal hyoid bone morphology
absent hyoid bone greater horns
abnormal jaw morphology
malocclusion
abnormal mandible morphology
mandibular coronoid process hypoplasia
premaxilla hypoplasia
maxilla hypoplasia
abnormal zygomatic bone morphology
cranioschisis
hemifacial hypoplasia
cleft palate
abnormal ear position
lowered ear position
Availability Mouse Genotype
Zic3Bn/Zic3Bn
Zic3tm1Bca/Zic3tm1Bca
Zic3tm1Jwb/Zic3tm1Jwb
Zic3tm1Bca/Y
Zic3tm1Jwb/Y
Zic3tm2.1Jwb/Y
Edil3Tg(Sox2-cre)1Amc/Edil3+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/19/2019
MGI 6.13
The Jackson Laboratory