Symbol
Name
ID

Ccr2
C-C motif chemokine receptor 2
MGI:106185

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes

Hypercalcemia

Decreased level of 1,5 anhydroglucitol in serum

Increased LDL cholesterol concentration

Hypercholesterolemia

Hypertriglyceridemia

Increased CSF protein concentration

Hyperglycemia

Glucose intolerance

Diabetes mellitus

Type II diabetes mellitus

Impaired glucose tolerance

Ketoacidosis

Joint swelling

Pleural effusion

Chylothorax

Fever

Hypothermia

Hepatic steatosis

Hypercalciuria

Scarring

Disease(s) Associated with CCR2

coronary artery disease

metabolic dysfunction-associated steatotic liver disease

sarcoidosis

type 1 diabetes mellitus

Mouse Phenotypes

abnormal response to cardiac infarction

abnormal vascular wound healing

decreased circulating creatinine level

decreased circulating alanine transaminase level

increased circulating alanine transaminase level

abnormal glucose homeostasis

abnormal lipid homeostasis

abnormal cholesterol homeostasis

abnormal urine protein level

increased physiological sensitivity to xenobiotic

decreased susceptibility to kidney reperfusion injury

abnormal wound healing

decreased susceptibility to injury

Availability

Mouse Genotype

Ccr2^{tm1.1(CCR2)Rodb}/Ccr2^{tm1.1(CCR2)Rodb}

Ccr2^tm1.1Mpa/Ccr2^tm1.1Mpa

Ccr2^tm1Blck/Ccr2^tm1Blck

Ccr2^tm1Ifc/Ccr2^tm1Ifc

Ccr2^tm1Mae/Ccr2^tm1Mae

Ccr2^tm1Mpa/Ccr2^tm1Mpa
Lyz2^tm1(cre)Ifo/Lyz2⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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