About   Help   FAQ
Symbol
Name
ID
Clcn2
chloride channel, voltage-sensitive 2
MGI:105061
Phenotype annotations related to nervous system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Absence seizure
Generalized myoclonic seizures
Generalized tonic-clonic seizures on awakening
Disease(s) Associated with CLCN2
idiopathic generalized epilepsy 11

Mouse Phenotypes
nervous system phenotype
abnormal blood-brain barrier function
abnormal microglial cell physiology
abnormal brain morphology
abnormal corpus callosum morphology
abnormal brain internal capsule morphology
abnormal brainstem morphology
abnormal cerebellum morphology
brain vacuoles
abnormal myelin sheath morphology
disorganized photoreceptor inner segment
abnormal photoreceptor outer segment morphology
disorganized photoreceptor outer segment
retinal photoreceptor degeneration
abnormal spinal cord morphology
neurodegeneration
axon degeneration
abnormal glial cell physiology
abnormal oligodendrocyte physiology
abnormal nerve conduction
Availability Mouse Genotype
Clcn2nmf240/Clcn2nmf240
Clcn2nmf289/Clcn2nmf289
Clcn2tm1Mlv/Clcn2tm1Mlv
Clcn2tm1Tjj/Clcn2tm1Tjj *
Clcn2tm2.1Tjj/Clcn2tm2.1Tjj *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/10/2019
MGI 6.14
The Jackson Laboratory