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Symbol
Name
ID
Gclm
glutamate-cysteine ligase, modifier subunit
MGI:104995
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
homeostasis/metabolism phenotype
increased susceptibility to neuronal excitotoxicity
decreased circulating cysteine level
decreased cysteine level
decreased glutathione level
increased circulating alanine transaminase level
increased susceptibility to xenobiotic induced morbidity/mortality
increased physiological sensitivity to xenobiotic
Availability Mouse Genotype
Gclmtm1Tdal/Gclmtm1Tdal
Gclmtm1Tjka/Gclmtm1Tjka *
Gclmtm1Tjka/Gclm+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory