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Symbol
Name
ID
Rest
RE1-silencing transcription factor
MGI:104897
Phenotype annotations related to hearing/vestibular/ear
Darker colors indicate more annotations
Human Phenotypes
Sensorineural hearing impairment
Disease(s) Associated with REST
autosomal dominant nonsyndromic deafness 27

Mouse Phenotypes
abnormal kinocilium morphology
abnormal outer hair cell stereociliary bundle morphology
cochlear inner hair cell degeneration
cochlear hair cell degeneration
abnormal utricle morphology
decreased threshold for auditory brainstem response
increased or absent threshold for auditory brainstem response
impaired hearing
deafness
Availability Mouse Genotype
Resttm1.2Bban/Rest+
Resttm2b(EUCOMM)Wtsi/Rest+
Resttm1.1Bban/Rest+
Gfi1tm1(cre)Gan/Gfi1+  (conditional)
Resttm1.1Bban/Rest+
Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/19/2020
MGI 6.15
The Jackson Laboratory