Symbol Name ID |
Tnf
tumor necrosis factor MGI:104798 |
Darker colors indicate more annotations |
Human Phenotypes | Splenomegaly |
Hepatosplenomegaly |
Abnormal abdomen morphology |
Hepatomegaly |
Delayed puberty |
Short stature |
Tall stature |
Decreased body mass index |
Increased body mass index |
Failure to thrive |
Small for gestational age |
Weight loss |
Obesity |
Growth delay |
Intrauterine growth retardation |
Disease(s) Associated with TNF | |||||||||||||||
beta thalassemia | |||||||||||||||
coronary artery disease | |||||||||||||||
cystic fibrosis | |||||||||||||||
Gaucher's disease | |||||||||||||||
Graves' disease | |||||||||||||||
hemochromatosis | |||||||||||||||
hypochromic microcytic anemia | |||||||||||||||
multiple myeloma | |||||||||||||||
pre-eclampsia | |||||||||||||||
rheumatoid arthritis | |||||||||||||||
systemic lupus erythematosus |
Mouse Phenotypes | increased heart weight |
alveolar process atrophy |
decreased embryo size |
increased body mass index |
decreased body weight |
weight loss |
increased body weight |
increased body length |
decreased susceptibility to diet-induced obesity |
increased susceptibility to diet-induced obesity |
enlarged liver |
increased liver weight |
enlarged spleen |
increased spleen weight |
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Availability | Mouse Genotype | ||||||||||||||
Lta/Tnftm1Eug/Lta/Tnftm1Eug | |||||||||||||||
Lta/Tnftm1Jods/Lta/Tnftm1Jods | |||||||||||||||
Tnfem4Boui/Tnfem4Boui | |||||||||||||||
Tnftm1Gkl/Tnftm1Gkl | |||||||||||||||
Tnftm2Gkl/Tnftm2Gkl | |||||||||||||||
Tnftm2Gkl/Tnf+ | |||||||||||||||
Tnftm2.1Gkl/Tnftm2.1Gkl Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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Tnftm2.1Gkl/Tnf+ Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/19/2024 MGI 6.23 |
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