|
Symbol Name ID |
Gpx4
glutathione peroxidase 4 MGI:104767 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | cellular phenotype |
abnormal sperm midpiece morphology |
abnormal sperm mitochondrial sheath morphology |
abnormal sperm principal piece morphology |
hairpin sperm flagellum |
kinked sperm flagellum |
abnormal photoreceptor connecting cilium morphology |
oligozoospermia |
abnormal sperm head morphology |
abnormal male germ cell morphology |
decreased male germ cell number |
decreased mitochondrial DNA content |
abnormal apoptosis |
increased neuron apoptosis |
increased hepatocyte apoptosis |
abnormal sperm motility |
asthenozoospermia |
abnormal cellular respiration |
abnormal mitochondrial physiology |
oxidative stress |
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| Availability | Mouse Genotype | ||||||||||||||||||||
| Gpx4tm1Yana/Gpx4tm1Yana | |||||||||||||||||||||
| Gpx4tm3Marc/Gpx4tm3Marc | * | ||||||||||||||||||||
| Gpx4tm1Ssd/Gpx4+ | |||||||||||||||||||||
| Gpx4tm4Marc/Gpx4+ | |||||||||||||||||||||
| Gpx4tm1.1Qra/Gpx4tm1.1Qra Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+ (conditional) |
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| Gpx4tm1Yana/Gpx4tm1Yana Tg(Crx-cre)1Tfur/0 Tg(Gpx4)#Yana/0 (conditional) |
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| Gpx4tm1Yana/Gpx4tm1Yana Tg(Gpx4)#Yana/0 Tg(Pgk2-cre)24Shb/0 (conditional) |
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| Gpx4tm2Marc/Gpx4tm2Marc Tg(Camk2a-cre)2Gsc/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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