Symbol Name ID |
Ppara
peroxisome proliferator activated receptor alpha MGI:104740 |
Darker colors indicate more annotations |
Human Phenotypes | Increased LDL cholesterol concentration |
Hypercholesterolemia |
Hypertriglyceridemia |
Glucose intolerance |
Diabetes mellitus |
Type II diabetes mellitus |
Impaired glucose tolerance |
Disease(s) Associated with PPARA | |||||||
coronary artery disease |
Mouse Phenotypes | decreased fatty acid oxidation |
increased susceptibility to diet-induced obesity |
impaired adaptive thermogenesis |
abnormal circulating glucose level |
decreased circulating glucose level |
hypoglycemia |
abnormal circulating insulin level |
increased circulating insulin level |
abnormal circulating ketone body level |
abnormal circulating HDL cholesterol level |
increased circulating cholesterol level |
increased circulating free fatty acids level |
increased circulating triglyceride level |
abnormal glucose homeostasis |
improved glucose tolerance |
decreased liver glycogen level |
increased insulin sensitivity |
insulin resistance |
increased skeletal muscle triglyceride level |
delayed wound healing |
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Availability | Mouse Genotype | ||||||||||||||||||||
Pparatm1Gonz/Pparatm1Gonz |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/19/2024 MGI 6.23 |
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