Symbol
Name
ID

Cdkn2a
cyclin dependent kinase inhibitor 2A
MGI:104738

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes

Increased circulating IgA level

Increased circulating IgG level

Decreased circulating antibody level

Paraproteinemia

Hypercalcemia

Elevated circulating creatinine concentration

Increased circulating ferritin concentration

Hyperproteinemia

Elevated circulating hepatic transaminase concentration

Increased circulating lactate dehydrogenase concentration

Diabetes mellitus

Pleural effusion

Fever

Abnormality of vitamin B12 metabolism

Increased level of L-fucose in urine

Elevated urinary homovanillic acid

Elevated urinary vanillylmandelic acid

Elevated urinary catecholamine level

Amyloidosis

Elevated circulating catecholamine level

Disease(s) Associated with CDKN2A

multiple myeloma

neuroblastoma

pancreatic cancer

pancreatic carcinoma

Mouse Phenotypes		increased circulating glucose level	decreased incidence of tumors by chemical induction	increased incidence of tumors by chemical induction
Availability	Mouse Genotype	increased circulating glucose level	decreased incidence of tumors by chemical induction	increased incidence of tumors by chemical induction
	Cdkn2a^tm1.1Brn/Cdkn2a^tm1.1Brn
	Cdkn2a^tm1Cjs/Cdkn2a^tm1Cjs
	Cdkn2a^tm1Nesh/Cdkn2a^tm1Nesh
	Cdkn2a^tm2.1Brn/Cdkn2a^tm2.1Brn
	Cdkn2a^tm2.1Rdp/Cdkn2a^tm2.1Rdp
	Cdkn2a^tm1Cjs/Cdkn2a⁺
	Tg(TTR-p19Cdkn2a)2Tvd/0

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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