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Symbol
Name
ID

Fgf9
fibroblast growth factor 9
MGI:104723

Phenotype annotations related to skeleton

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Dolichocephaly	Limited interphalangeal movement	Broad thumb	Broad hallux	Hallux varus	Cutaneous syndactyly of toes	Metatarsal synostosis	Humeroradial synostosis	Metacarpal synostosis	Cubitus valgus
Disease(s) Associated with FGF9
multiple synostoses syndrome 3

Mouse Phenotypes

skeleton phenotype

enlarged Meckel's cartilage

abnormal occipital bone morphology

abnormal temporal bone morphology

abnormal incisor morphology

misaligned incisors

abnormal tooth development

small mandible

short mandible

abnormal premaxilla morphology

short premaxilla

short nasal bone

abnormal palate bone morphology

abnormal humerus morphology

increased diameter of humerus

short humerus

abnormal radius morphology

short radius

increased diameter of radius

short ulna

increased diameter of ulna

abnormal knee joint morphology

short femur

increased diameter of femur

increased diameter of fibula

short fibula

increased diameter of tibia

short tibia

caudal vertebral fusion

abnormal long bone morphology

abnormal sternum morphology

short sternum

wide ribs

abnormal coccyx morphology

abnormal intervertebral disk morphology

abnormal vertebral arch morphology

fusion of vertebral arches

vertebral fusion

abnormal cartilage development

increased chondrocyte number

abnormal joint morphology

calcified joint

fused joints

synostosis

premature coronal suture closure

premature sagittal suture closure

delayed bone ossification

increased bone ossification

premature bone ossification

abnormal cartilage physiology

Availability

Mouse Genotype

Fgf9^Aca12/Fgf9^Aca12

*

Fgf9^Eks/Fgf9^Eks

Fgf9^tm1.2Zqch/Fgf9^tm1.2Zqch

Fgf9^tm1Zgwg/Fgf9^tm1Zgwg

Fgf9^Eks/Fgf9⁺

Fgf9^Eks/Fgf9^tm1Dor

Fgf9^tm1.2Zqch/Fgf9⁺

Fgf9^tm1Dor/Fgf9⁺

Fgf9^tm1Zgwg/Fgf9⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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