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Symbol
Name
ID
Tle4
transducin-like enhancer of split 4
MGI:104633
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations

Mouse Phenotypes
increased thymocyte apoptosis
abnormal thymus morphology
thymus atrophy
thymus hypoplasia
decreased DN2 thymocyte number
enlarged spleen
decreased common myeloid progenitor cell number
abnormal lymphopoiesis
decreased pre-pro B cell number
decreased double-positive T cell number
decreased bone marrow cell number
decreased follicular B cell number
decreased B cell number
increased NK T cell number
decreased lymphocyte cell number
decreased leukocyte cell number
decreased hematopoietic stem cell number
abnormal spleen morphology
spleen hypoplasia
abnormal spleen B cell follicle morphology
abnormal hematopoietic stem cell physiology
Availability Mouse Genotype
Tle4em1(IMPC)Mbp/Tle4em1(IMPC)Mbp
Tle4tm1.2Dasw/Tle4tm1.2Dasw

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/17/2022
MGI 6.19
The Jackson Laboratory