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Symbol
Name
ID
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
MGI:104556
Phenotype annotations related to neoplasm
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
neoplasm
increased sebaceous gland adenoma incidence
increased Leydig cell tumor incidence
increased T cell derived lymphoma incidence
increased incidence of tumors by chemical induction
increased skin tumor incidence
increased hepatocellular carcinoma incidence
increased metastatic potential
abnormal tumor incidence
decreased lymphoma incidence
increased B cell derived lymphoma incidence
increased histiocytic sarcoma incidence
increased malignant tumor incidence
increased carcinoma incidence
increased lung carcinoma incidence
increased squamous cell carcinoma incidence
increased hemangiosarcoma incidence
decreased incidence of tumors by ionizing radiation induction
increased incidence of tumors by ionizing radiation induction
increased urinary system tumor incidence
increased tumor incidence
Availability Mouse Genotype
Cdkn1atm1(HBsAg)Xya/Cdkn1atm1(HBsAg)Xya
Cdkn1atm1Led/Cdkn1atm1Led
Cdkn1atm1Tyj/Cdkn1atm1Tyj
Cdkn1atm2(HBx)Xya/Cdkn1atm2(HBx)Xya
Cdkn1atm1(HBsAg)Xya/Cdkn1a+
Cdkn1atm1Tyj/Cdkn1a+
Cdkn1atm2(HBx)Xya/Cdkn1a+
Cdkn1atm1Led/Cdkn1atm1Led
Tg(Upk2-cre)6Xrw/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory