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Symbol
Name
ID
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
MGI:104556
Phenotype annotations related to cellular
Darker colors indicate more annotations

Mouse Phenotypes
abnormal chromosome number
abnormal cell physiology
abnormal DNA replication
abnormal cell cycle
abnormal cell cycle checkpoint function
increased sensitivity to induced cell death
increased cellular sensitivity to gamma-irradiation
increased cellular sensitivity to ultraviolet irradiation
impaired macrophage chemotaxis
increased T cell proliferation
increased fibroblast proliferation
abnormal neuronal precursor proliferation
decreased hepatocyte proliferation
increased cell proliferation
delayed cellular replicative senescence
Availability Mouse Genotype
Cdkn1atm1Led/Cdkn1atm1Led
Cdkn1atm1Tyj/Cdkn1atm1Tyj
Tg(Ttr-Cdkn1a)36Tvd/?

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory