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Symbol
Name
ID

Brca1
breast cancer 1, early onset
MGI:104537

Phenotype annotations related to embryo

Darker colors indicate more annotations

Human Phenotypes	Oligohydramnios
Disease(s) Associated with BRCA1	Oligohydramnios
Fanconi anemia

Mouse Phenotypes

abnormal developmental patterning

embryonic growth retardation

decreased embryo size

abnormal embryonic tissue morphology

abnormal egg cylinder morphology

absent egg cylinders

abnormal axial mesoderm morphology

absent mesoderm

abnormal embryonic neuroepithelial layer differentiation

open neural tube

spina bifida

abnormal primitive streak formation

failure of primitive streak formation

incomplete somite formation

enlarged tail bud

disorganized embryonic tissue

abnormal embryonic-extraembryonic boundary morphology

absent trophoblast giant cells

abnormal extraembryonic tissue morphology

absent amniotic folds

abnormal parietal endoderm morphology

abnormal trophoblast layer morphology

disorganized extraembryonic tissue

abnormal visceral endoderm morphology

Availability

Mouse Genotype

Brca1^tm1.1Jjon/Brca1^tm1.1Jjon

Brca1^tm1Arge/Brca1^tm1Arge

Brca1^tm1Bhk/Brca1^tm1Bhk

Brca1^tm1Cxd/Brca1^tm1Cxd

Brca1^tm1Mak/Brca1^tm1Mak

Brca1^tm1Rfo/Brca1^tm1Rfo

Brca1^tm1Whl/Brca1^tm1Whl

Brca1^tm2.1Cxd/Brca1^tm2.1Cxd

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23