|
Symbol Name ID |
Pms2
PMS1 homolog2, mismatch repair system component MGI:104288 |
| Darker colors indicate more annotations |
| Human Phenotypes | Leukemia |
Hematological neoplasm |
Lymphoma |
Non-Hodgkin lymphoma |
T-cell lymphoma |
Adenoma sebaceum |
Salivary gland neoplasm |
Breast carcinoma |
Neoplasm of the rectum |
Adenocarcinoma of the colon |
Hereditary nonpolyposis colorectal carcinoma |
Adenomatous colonic polyposis |
Colon cancer |
Intestinal polyposis |
Neoplasm of the stomach |
Neoplasm of the liver |
Hepatocellular carcinoma |
Neoplasm of the pancreas |
Pancreatic adenocarcinoma |
Adenocarcinoma of the small intestine |
Pituitary adenoma |
Neoplasm of the thyroid gland |
Ovarian neoplasm |
Dysgerminoma |
Ovarian papillary adenocarcinoma |
Endometrial carcinoma |
Renal neoplasm |
Malignant genitourinary tract tumor |
Urinary tract neoplasm |
Bladder neoplasm |
Transitional cell carcinoma of the bladder |
Neoplasm of the skin |
Basal cell carcinoma |
Plexiform neurofibroma |
Rhabdomyosarcoma |
Neoplasm of the skeletal system |
Astrocytoma |
Pleomorphic xanthoastrocytoma |
Ependymoma |
Glioblastoma multiforme |
Oligodendroglioma |
Benign neoplasm of the central nervous system |
Medulloblastoma |
Neuroblastoma |
Laryngeal carcinoma |
| Disease(s) Associated with PMS2 | |||||||||||||||||||||||||||||||||||||||||||||
| hereditary nonpolyposis colorectal cancer type 4 | |||||||||||||||||||||||||||||||||||||||||||||
| Lynch syndrome | |||||||||||||||||||||||||||||||||||||||||||||
| mismatch repair cancer syndrome | |||||||||||||||||||||||||||||||||||||||||||||
| ovarian cancer | |||||||||||||||||||||||||||||||||||||||||||||
| urinary bladder cancer |
| Mouse Phenotypes | increased T cell derived lymphoma incidence |
increased incidence of tumors by chemical induction |
increased liver adenoma incidence |
increased hemangioma incidence |
increased lymphoma incidence |
increased B cell derived lymphoma incidence |
increased carcinoma incidence |
increased adenocarcinoma incidence |
increased sarcoma incidence |
|
| Availability | Mouse Genotype | |||||||||
| Pms2tm1.1Wed/Pms2tm1.1Wed | ||||||||||
| Pms2tm1Lisk/Pms2tm1Lisk | ||||||||||
| Pms2tm1Lisk/Pms2+ | ||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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