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Symbol
Name
ID
Hand2
heart and neural crest derivatives expressed 2
MGI:103580
Phenotype annotations related to craniofacial
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
craniofacial phenotype
abnormal pharyngeal arch artery morphology
abnormal first pharyngeal arch artery morphology
absent second pharyngeal arch artery
abnormal craniofacial bone morphology
abnormal jaw morphology
mandible hypoplasia
short mandible
abnormal primary and secondary palatal fusion
abnormal palatal shelf elevation
failure of palatal shelf elevation
palatal shelves fail to meet at midline
decreased palatal shelf size
abnormal first pharyngeal arch morphology
absent pharyngeal arches
pharyngeal arch hypoplasia
abnormal facial morphology
cleft secondary palate
tongue hypoplasia
Availability Mouse Genotype
Hand2tm1.2Zllr/Hand2tm1.2Zllr
Hand2tm1Dsr/Hand2tm1Dsr
Hand2tm1Majh/Hand2tm1Majh
Hand2tm2Eno/Hand2tm2Eno
Hand2tm1Cse/Hand2tm1Dsr
Hand2tm1.1Majh/Hand2tm1.1Majh
H2az2Tg(Wnt1-cre)11Rth/H2az2+  (conditional)
Hand2tm1Cse/Hand2tm1Cse
H2az2Tg(Wnt1-cre)11Rth/H2az2+  (conditional)
*
Hand2tm1Cse/Hand2tm1Cse
Osr2tm2(cre)Jian/Osr2+  (conditional)
Hand2tm1Cse/Hand2tm1Cse
Tg(Pitx2-cre)1Ych/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory