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Symbol
Name
ID
Hand1
heart and neural crest derivatives expressed 1
MGI:103577
Phenotype annotations related to craniofacial
Darker colors indicate more annotations

Mouse Phenotypes
abnormal craniofacial morphology
abnormal sagittal suture morphology
abnormal basicranium morphology
basisphenoid bone hypoplasia
small frontal bone
frontal bone hypoplasia
interparietal bone hypoplasia
abnormal alisphenoid bone morphology
pterygoid bone hypoplasia
absent temporal bone squamous part
squamosal bone hypoplasia
small mandible
mandible hypoplasia
abnormal maxilla morphology
decreased maxillary shelf size
premaxilla hypoplasia
short premaxilla
absent nasal bone
small nasal bone
nasal bone hypoplasia
decreased palatine bone horizontal plate size
zygomatic bone hypoplasia
absent middle ear ossicles
middle ear ossicle hypoplasia
abnormal craniofacial development
short Meckel's cartilage
abnormal Reichert's cartilage morphology
abnormal maxillary prominence morphology
abnormal nasal capsule morphology
abnormal palate development
abnormal secondary palate development
abnormal palatal shelf fusion at midline
abnormal pharyngeal arch morphology
abnormal tongue morphology
absent nasal septum
midline facial cleft
Availability Mouse Genotype
Hand1tm2.1(Hand1)Abfi/Hand1tm2.1(Hand1)Abfi
Hand1tm2.1Jcc/Hand1tm2.1Jcc
Hand1tm1Jcc/Hand1tm2.1Jcc
Hand1tm2.1Jcc/Hand1+
Hand1tm2Eno/Hand1tm3Abfi
Tg(Wnt1-cre)2Sor/0  (conditional)
Hand1tm2Eno/Hand1tm4Abfi
Tg(Wnt1-cre)2Sor/0  (conditional)
Hand1tm3Abfi/Hand1+
Tg(Wnt1-cre)2Sor/0  (conditional)
Hand1tm3Abfi/Hand1+
Tg(Mpz-cre)94Imeg/0  (conditional)
Hand1tm4Abfi/Hand1+
Tg(Wnt1-cre)2Sor/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory