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Symbol
Name
ID
Yap1
yes-associated protein 1
MGI:103262
Phenotype annotations related to renal/urinary system
Darker colors indicate more annotations
Human Phenotypes
Hematuria
Disease(s) Associated with YAP1
uveal coloboma-cleft lip and palate-intellectual disability

Mouse Phenotypes
abnormal kidney cortex morphology
podocyte foot process effacement
abnormal renal glomerulus morphology
decreased renal glomerulus number
abnormal kidney development
abnormal metanephros morphology
abnormal nephrogenic zone morphology
abnormal kidney medulla morphology
abnormal kidney papilla morphology
renal hypoplasia
abnormal renal tubule morphology
abnormal loop of Henle morphology
abnormal proximal convoluted tubule morphology
decreased renal tubule number
impaired branching involved in ureteric bud morphogenesis
anuria
Availability Mouse Genotype
Yap1tm1Hmc/Yap1tm1Hmc
Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory