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Symbol
Name
ID

Vhl
von Hippel-Lindau tumor suppressor
MGI:103223

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Hypercalcemia	Elevated circulating hepatic transaminase concentration	Diabetes mellitus	Proteinuria	Elevated urinary norepinephrine level	Elevated circulating erythropoietin concentration
Disease(s) Associated with VHL	Hypercalcemia	Elevated circulating hepatic transaminase concentration	Diabetes mellitus	Proteinuria	Elevated urinary norepinephrine level	Elevated circulating erythropoietin concentration
familial erythrocytosis 2
pancreatic cancer
pheochromocytoma

Mouse Phenotypes		decreased circulating creatinine level	decreased blood urea nitrogen level	increased blood urea nitrogen level	increased circulating erythropoietin level	edema	albuminuria	increased incidence of tumors by chemical induction	decreased susceptibility to kidney reperfusion injury
Availability	Mouse Genotype	decreased circulating creatinine level	decreased blood urea nitrogen level	increased blood urea nitrogen level	increased circulating erythropoietin level	edema	albuminuria	increased incidence of tumors by chemical induction	decreased susceptibility to kidney reperfusion injury
	Vhl^tm1.1Wkr/Vhl⁺
	Vhl^tm1Wml/Vhl⁺
	Vhl^tm1Jae/Vhl^tm1Jae Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 (conditional)
	Vhl^tm1Jae/Vhl^tm1Jae Tg(NPHS2-cre)295Lbh/? (conditional)
	Vhl^tm1Lss/Vhl^tm1.1Lss Tg(CAG-cre/Esr1*)1Lbe/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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