Symbol
Name
ID

Vegfa
vascular endothelial growth factor A
MGI:103178

Phenotype annotations related to craniofacial

Darker colors indicate more annotations

Human Phenotypes

Coronal craniosynostosis

Decreased calvarial ossification

Micrognathia

Malar flattening

Midface retrusion

Facial palsy

White oral mucosal macule

Gingival overgrowth

High palate

High, narrow palate

Natal tooth

Lisch nodules

Retinal hamartoma

Disease(s) Associated with VEGFA

pre-eclampsia

pseudoxanthoma elasticum

vestibular schwannomatosis

Mouse Phenotypes

abnormal pharyngeal arch artery morphology

abnormal fourth pharyngeal arch artery morphology

abnormal sixth pharyngeal arch artery morphology

abnormal third pharyngeal arch artery morphology

abnormal craniofacial morphology

abnormal coronal suture morphology

absent incisors

abnormal mandible morphology

short mandible

abnormal maxilla morphology

abnormal palatal mesenchymal cell proliferation

abnormal secondary palate development

abnormal palatal shelf bone ossification

abnormal palatal shelf elevation

palatal shelves fail to meet at midline

decreased palatal shelf size

palatal shelf hypoplasia

abnormal pharyngeal arch morphology

pharyngeal arch hypoplasia

cleft palate

Availability

Mouse Genotype

Vegfa^tm1Pec/Vegfa^tm1Pec

Vegfa^tm4Pec/Vegfa^tm4Pec

Vegfa^tm1Gne/Vegfa⁺

Vegfa^tm2Gne/Vegfa^tm2Gne
E2f1^{Tg(Wnt1-cre)2Sor}/E2f1⁺ (conditional)

Vegfa^tm2Gne/Vegfa^tm2.1Nagy
Tg(Nes-cre)1Kln/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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