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Symbol
Name
ID
Stat4
signal transducer and activator of transcription 4
MGI:103062
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Increased circulating IgA level
Increased circulating IgM level
Abnormality of chromosome stability
Chromosome breakage
Abnormality of metabolism/homeostasis
Conjugated hyperbilirubinemia
Abnormal circulating lipid concentration
Hypercholesterolemia
Hypoalbuminemia
Elevated gamma-glutamyltransferase level
Elevated circulating alkaline phosphatase concentration
Fever
Hematuria
Pyuria
Decreased level of D-mannose in urine
Proteinuria
Ascites
Disease(s) Associated with STAT4
Behcet's disease
IgA glomerulonephritis
primary biliary cholangitis
Sjogren's syndrome
systemic lupus erythematosus
systemic scleroderma

Mouse Phenotypes
abnormal insulin secretion
abnormal circulating glucose level
decreased circulating interferon-gamma level
increased circulating interleukin-12 level
decreased circulating interleukin-2 level
Availability Mouse Genotype
Stat4ity14/Stat4ity14
Stat4tm1Gru/Stat4tm1Gru
Stat4tm1Jni/Stat4tm1Jni
Stat4tm1Gru/Stat4+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory