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Symbol
Name
ID

Stat3
signal transducer and activator of transcription 3
MGI:103038

Phenotype annotations related to neoplasm

Darker colors indicate more annotations

Human Phenotypes	Lymphoma	Breast carcinoma	Prostate cancer	Dysgerminoma	Ovarian papillary adenocarcinoma	Renal cell carcinoma	Squamous cell carcinoma
Disease(s) Associated with STAT3	Lymphoma	Breast carcinoma	Prostate cancer	Dysgerminoma	Ovarian papillary adenocarcinoma	Renal cell carcinoma	Squamous cell carcinoma
breast cancer
head and neck squamous cell carcinoma
hyper IgE recurrent infection syndrome 1
ovarian cancer
prostate cancer
renal cell carcinoma

Mouse Phenotypes		increased gastrointestinal tumor incidence	decreased incidence of tumors by chemical induction	increased incidence of tumors by chemical induction	increased carcinoma incidence
Availability	Mouse Genotype	increased gastrointestinal tumor incidence	decreased incidence of tumors by chemical induction	increased incidence of tumors by chemical induction	increased carcinoma incidence
	Stat3^tm1Dlv/Stat3^tm1Dlv Tg(Csf1r-icre)1Jwp/0 (conditional)
	Stat3^tm1Vpo/Stat3^tm1Vpo Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ (conditional)
	Stat3^tm2Aki/Stat3^tm2Aki Tg(KRT5-cre/ERT2)AJdg/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23