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Symbol
Name
ID

Stat3
signal transducer and activator of transcription 3
MGI:103038

Phenotype annotations related to integument

Darker colors indicate more annotations

Human Phenotypes

Breast carcinoma

Erythema

Cutaneous abscess

Recurrent cutaneous abscess formation

Eczematoid dermatitis

Erythema nodosum

Chronic mucocutaneous candidiasis

Chronic oral candidiasis

Skin rash

Abnormal hair morphology

Patchy alopecia

Dystrophic fingernails

Paronychia

Generalized abnormality of skin

Papule

Skin ulcer

Skin vesicle

Pruritus

Squamous cell carcinoma

Disease(s) Associated with STAT3

Behcet's disease

breast cancer

head and neck squamous cell carcinoma

hyper IgE recurrent infection syndrome 1

ovarian cancer

Mouse Phenotypes		decreased keratinocyte migration	dermatitis	abnormal hair follicle morphology	decreased hair follicle number	abnormal hair cycle anagen phase	abnormal epidermal layer morphology	hyperkeratosis	acanthosis	spontaneous skin ulceration	skin fibrosis
Availability	Mouse Genotype	decreased keratinocyte migration	dermatitis	abnormal hair follicle morphology	decreased hair follicle number	abnormal hair cycle anagen phase	abnormal epidermal layer morphology	hyperkeratosis	acanthosis	spontaneous skin ulceration	skin fibrosis
	Stat3^tm2Aki/Stat3^tm2Aki Tg(KRT5-cre/ERT2)AJdg/0 (conditional)
	Stat3^tm2Aki/Stat3^tm2Aki Tg(KRT5-cre)1Tak/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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