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Symbol
Name
ID
Tpp2
tripeptidyl peptidase II
MGI:102724
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
increased T cell apoptosis
thymus atrophy
abnormal CD4-positive T cell differentiation
abnormal CD8-positive, alpha-beta T cell differentiation
increased double-negative T cell number
decreased double-positive T cell number
increased B cell number
decreased CD8-positive, alpha-beta T cell number
increased memory T cell number
decreased T cell number
increased T cell number
increased single-positive T cell number
decreased leukocyte cell number
abnormal spleen morphology
increased spleen red pulp amount
enlarged spleen
abnormal splenic cell ratio
abnormal lymphocyte physiology
abnormal cytotoxic T cell physiology
abnormal immune system cell morphology
abnormal immune system organ morphology
enlarged lymph nodes
abnormal antigen presentation
abnormal level of surface class I molecules
increased autoantibody level
increased anti-nuclear antigen antibody level
Availability Mouse Genotype
Tpp2Gt(OST432061)Lex/Tpp2Gt(OST432061)Lex
Tpp2tm1.1Gnie/Tpp2tm1.1Gnie

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory