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Symbol
Name
ID
Akr1b7
aldo-keto reductase family 1, member B7
MGI:101918
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
homeostasis/metabolism phenotype
increased susceptibility to diet-induced obesity
decreased fasting circulating glucose level
increased circulating insulin level
increased circulating leptin level
decreased circulating progesterone level
increased circulating progesterone level
increased circulating glycerol level
increased circulating triglyceride level
decreased energy expenditure
decreased respiratory quotient
insulin resistance
increased circulating adiponectin level
increased liver triglyceride level
abnormal interferon level
abnormal interleukin level
decreased lipogenesis
increased incidence of tumors by chemical induction
Availability Mouse Genotype
Akr1b7tm1.1Anm/Akr1b7tm1.1Anm *
Akr1b7tm1.1Fth/Akr1b7tm1.1Fth
Akr1b8tm1.1(KOMP)Vlcg/Akr1b8tm1.1(KOMP)Vlcg
Akr1b8tm1Dgen/Akr1b8tm1Dgen

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory