|
Symbol Name ID |
Isl1
ISL1 transcription factor, LIM/homeodomain MGI:101791 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Hypertelorism |
| Disease(s) Associated with ISL1 | |
| double outlet right ventricle |
| Mouse Phenotypes | vision/eye phenotype |
increased retina apoptosis |
abnormal optic nerve innervation |
decreased amacrine cell number |
decreased retina ganglion cell number |
abnormal retina bipolar cell morphology |
abnormal retina ganglion cell morphology |
retina ganglion cell degeneration |
abnormal optic nerve morphology |
optic nerve degeneration |
optic nerve hypoplasia |
microphthalmia |
thin retina inner nuclear layer |
thin retina inner plexiform layer |
abnormal retina outer plexiform layer morphology |
|
| Availability | Mouse Genotype | |||||||||||||||
| Isl1tm1.1Whk/Isl1tm1.1Whk Tg(Six3-cre)69Frty/0 (conditional) |
* | |||||||||||||||
| Isl1tm2Gan/Isl1tm2Gan Tg(Six3-cre)69Frty/? (conditional) |
||||||||||||||||
| Isl1tm1Gan/Isl1tm2Gan Tg(Six3-cre)69Frty/? (conditional) |
||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/16/2024 MGI 6.23 |
|
|
|
||
Analysis Tools