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Mouse Models of systemic lupus erythematosus
Mouse Models All mouse models of systemic lupus erythematosus (Disease Ontology ID: DOID:9074)

        Allelic Composition Genetic Background Reference Phenotypes
      systemic lupus erythematosus Fcgr2btm1Ttk/Fcgr2btm1Ttk B6.129S4-Fcgr2btm1Ttk J:64152 View
systemic lupus erythematosus Fcgr2btm1Ttk/Fcgr2btm1Ttk
Traf3ip2tm1Sbn/Traf3ip2+
involves: 129 * 129S4/SvJae * C57BL/6 J:191090 View
systemic lupus erythematosus Dnase1tm1Tmo/Dnase1tm1Tmo involves: 129P2/OlaHsd * C57BL/6 J:62549 View
      systemic lupus erythematosus Traf3ip2tm1.1Lix/Traf3ip2tm1.1Lix B6.129-Traf3ip2tm1.1Lix J:187766 View
systemic lupus erythematosus Trove2tm1Woln/Trove2tm1Woln B6.129S1-Trove2tm1Woln J:84627 View
systemic lupus erythematosus Pdcd1tm1Hon/Pdcd1tm1Hon B6.129S2-Pdcd1tm1Hon J:78802 View
systemic lupus erythematosus Ptpn22tm2Achn/Ptpn22tm2Achn
Ptprctm1Weis/Ptprctm1Weis
B6.Cg-Ptprctm1Weis Ptpn22tm2Achn J:147129 View
systemic lupus erythematosus Rassf5tm1Kina/Rassf5tm1Kina B6.Cg-Rassf5tm1Kina J:168749 View
systemic lupus erythematosus Jak1M1Mhda/Jak1+ C3HeB/FeJ-Jak1M1Mhda J:199153 View
systemic lupus erythematosus Tg(Igh-V-CD40lg)#Tsub/0 C57BL/6-Tg(Igh-V-CD40lg)#Tsub J:128824 View
systemic lupus erythematosus Pdcd1tm1Hon/Pdcd1tm1Hon C.129S2(B6)-Pdcd1tm1Hon J:66979 View
systemic lupus erythematosus Ifih1Rgsc422/Ifih1Rgsc422 D2JJcl.B6JJcl-Ifih1Rgsc422 J:209917 View
systemic lupus erythematosus Ifih1Rgsc422/Ifih1+ D2JJcl.B6JJcl-Ifih1Rgsc422 J:209917 View
systemic lupus erythematosus Cdkn1atm1Led/Cdkn1atm1Led
Gadd45atm1Ajf/Gadd45atm1Ajf
either: (involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6) J:76041 View
systemic lupus erythematosus Gadd45atm1Ajf/Gadd45atm1Ajf either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129X1/SvJ * C57BL/6) J:76041 View
systemic lupus erythematosus Rc3h1san/Rc3h1san either: C57BL/6JSfdAnu-Rc3h1san/Anu or (involves: C57BL/6JSfdAnu * CBA/Ca) J:98938 View
systemic lupus erythematosus KitW-sh/KitW-sh
Lyntm1Ard/Lyntm1Ard
involves: 101 * 129P2/OlaHsd * C3H/HeH J:161523 View
systemic lupus erythematosus Rasgrp1lag/Rasgrp1lag involves: 129 * C57BL/6 J:85189 View
systemic lupus erythematosus Junbtm3Wag/Junbtm3Wag
Tg(KRT5-cre)1Tak/0
involves: 129/Sv * 129P2/OlaHsd * C3H * C57BL/6 J:155575 View
systemic lupus erythematosus Cd19tm1(cre)Cgn/Cd19+
Ep300tm2Reck/Ep300+
involves: 129/Sv * 129P2/OlaHsd * C57BL/6 J:147840 View
systemic lupus erythematosus Polbtm1.1Jbsw/Polbtm1.1Jbsw involves: 129/Sv * C57BL/6 J:206872 View
systemic lupus erythematosus C1qatm1Mjw/C1qatm1Mjw involves: 129P2/Ola * 129S/SvEv * C57BL/6 J:47315 View
systemic lupus erythematosus Lyntm1Ard/Lyntm1Ard involves: 129P2/OlaHsd J:161523 View
systemic lupus erythematosus Rxratm1Krc/Rxratm1Krc
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 J:168799 View
systemic lupus erythematosus Ppargtm1.1Gonz/Ppargtm1.1Gonz
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 J:168799 View
systemic lupus erythematosus Man2a1tm1Jxm/Man2a1tm1Jxm involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:74579 View
systemic lupus erythematosus Prdm1tm1Clme/Prdm1tm1Clme
Tg(Itgax-cre)1-1Reiz/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA J:178876 View
systemic lupus erythematosus Trove2tm1Woln/Trove2tm1Woln involves: 129S1/Sv * C57BL/6 J:84627 View
systemic lupus erythematosus Trove2tm1Woln/Trove2+ involves: 129S1/Sv * C57BL/6 J:84627 View
systemic lupus erythematosus Pdcd1tm1Hon/Pdcd1tm1Hon involves: 129S2/SvPas * C57BL/6 J:50688 View
systemic lupus erythematosus Ikzf3tm1Kge/Ikzf3tm1Kge involves: 129S4/SvJae * C57BL/6 J:50626, J:81805 View
systemic lupus erythematosus Mta2tm1.1Yzha/Mta2tm1.1Yzha involves: 129S4/SvJae * C57BL/6 * FVB/N J:137101 View
systemic lupus erythematosus C4btm1Crr/C4btm1Crr involves: 129S4/SvJae * C57BL/6J J:111811 View
systemic lupus erythematosus Def6Gt(OST307148)Lex/Def6Gt(OST307148)Lex involves: 129S5/SvEvBrd * C57BL/6 J:106469 View
systemic lupus erythematosus Cdkn1atm1Led/Cdkn1atm1Led involves: 129S6/SvEvTac J:76041 View
systemic lupus erythematosus Ptprctm1Weis/Ptprctm1Weis involves: 129X1/SvJ * C57BL/6 J:66501 View
systemic lupus erythematosus Ptprctm1Weis/Ptprc+ involves: 129X1/SvJ * C57BL/6 J:66501 View
systemic lupus erythematosus Tnfrsf13btm1Vmd/Tnfrsf13btm1Vmd involves: C57BL/6 J:82331 View
systemic lupus erythematosus Tg(Tlr7)1Boll/0 involves: C57BL/6 J:193610 View
systemic lupus erythematosus Ccr2tm1Blck/Ccr2tm1Blck
Faslpr/Faslpr
MRL.Cg-Ccr2tm1Blck Faslpr J:113343 View
systemic lupus erythematosus Faslpr/Faslpr
Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+
MRL.Cg-Faslpr Igh-Jtm2(3H9-VDJ*)Mwg J:131138 View
systemic lupus erythematosus Faslpr/Faslpr
Tlr9tm1Aki/Tlr9tm1Aki
MRL.Cg-Tlr9tm1Aki Faslpr J:113557 View
systemic lupus erythematosus Faslpr/Faslpr
Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
MRL.Cg-Tnfrsf9tm1Byk Faslpr J:120559 View
systemic lupus erythematosus Faslpr/Faslpr MRL/Mp-Faslpr J:27634, J:28885, J:108760, J:131138 View
Transgenes and
Other Mutations
     systemic lupus erythematosus X/Yaa (NZB x BXSB)F1 J:6235 View
systemic lupus erythematosus X/Yaa (NZW x BXSB)F1 J:7276 View
systemic lupus erythematosus X/Yaa (NZW x SB)F1 J:7276 View
systemic lupus erythematosus Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+ B6.129P2-Igh-Jtm2(3H9-VDJ*)Mwg J:142389 View
systemic lupus erythematosus Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom
Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+
B6.129P2-Tcrbtm1Mom Igh-Jtm2(3H9-VDJ*)Mwg Tcrdtm1Mom J:142389 View
systemic lupus erythematosus Cd4tm1Mak/Cd4tm1Mak
Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+
B6.Cg-Cd4tm1Mak Igh-Jtm2(3H9-VDJ*)Mwg J:142389 View
systemic lupus erythematosus Tg(ACTB-TNFRSF6B)754Jwu/? B6.Cg-Tg(Actb-TNFRSF6B)754Jwu J:148162 View
systemic lupus erythematosus X/Yaa BXSB/MpJ J:6235, J:108760, J:7308 View
systemic lupus erythematosus X/Yaa BXSB/MpJScr J:10973 View
Additional Complex Models     systemic lupus erythematosus Csf2tm1Dran/Csf2tm1Dran
Il3tm1Glli/Il3tm1Glli
B6.129S2-Csf2tm1Dran Il3tm1Glli J:83086 View
systemic lupus erythematosus Ightm1(Igh564)Tik/Ightm1(Igh564)Tik
Igktm1(Igk564)Tik/Igktm1(Igk564)Tik
B6.129S4-Igktm1(Igk564)Tik Ightm1(Igh564)Tik J:113555 View
systemic lupus erythematosus Apoetm1Unc/Apoetm1Unc
Faslgld/Faslgld
B6.Cg-Faslgld Apoetm1Unc J:91058, J:200141 View
systemic lupus erythematosus Psen1tm1Bdes/Psen1+
Psen2tm1Bdes/Psen2tm1Bdes
involves: 129P2/OlaHsd J:91235 View
Disease phenotype
not observed
No similarity to the expected human disease phenotype was found.

        Allelic Composition Genetic Background Reference Phenotypes
NOT Models     systemic lupus erythematosus Tlr7tm1Flv/Y
X/Yaa
B6.Cg-Tlr7tm1Flv Yaa J:127600 View
systemic lupus erythematosus Csf2tm1Dran/Csf2tm1Dran
Ifngtm1Ts/Ifngtm1Ts
Il3tm1Glli/Il3tm1Glli
involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6 J:83086 View

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last database update
04/18/2017
MGI 6.08
The Jackson Laboratory