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Mouse Models of schizophrenia
Mouse Models All mouse models of schizophrenia (Disease Ontology ID: DOID:5419)

        Allelic Composition Genetic Background Reference Phenotypes
      schizophrenia Disc1tm1(DISC1/DISC1FP1,DISC1FP1/DISC1)Xzho/Disc1del 129S2/SvPasCrl-Disc1del Disc1tm1(DISC1/DISC1FP1,DISC1FP1/DISC1)Xzho J:214737 View
schizophrenia Disc1tm1Kara/Disc1tm1Kara B6.129S6-Disc1tm1Kara J:107244 View
schizophrenia Disc1tm1Kara/Disc1+ B6.129S6-Disc1tm1Kara J:107244 View
schizophrenia Disc1Rgsc1390/Disc1Rgsc1390 B6.Cg-Disc1Rgsc1390 J:120634 View
schizophrenia Dtnbp1sdy/Dtnbp1sdy B6J.D2-Dtnbp1sdy J:197066, J:223954 View
schizophrenia Disc1m1H/Disc1m1H B6N.C(C3H)-Disc1m1H J:229661 View
schizophrenia Tg(Camk2a-DISC1)10Asaw/0 C57BL/6-Tg(Camk2a-DISC1)10Asaw J:124683, J:194985 View
schizophrenia Tg(Camk2a-DISC1)37Asaw/0 C57BL/6-Tg(Camk2a-DISC1)37Asaw J:124683, J:194985 View
schizophrenia Tg(Camk2a-DISC1)37Asaw/Tg(Camk2a-DISC1)37Asaw C57BL/6-Tg(Camk2a-DISC1)37Asaw J:194985 View
schizophrenia Dtnbp1sdy/Dtnbp1sdy DBA/2J-Dtnbp1sdy/J J:143912 View
schizophrenia Akt1tm1Mbb/Akt1tm1Mbb involves: 129P2/OlaHsd * C57BL/6 J:185487 View
schizophrenia Shank3tm4.1Gfng/Shank3tm4.1Gfng involves: 129S1/Sv * 129X1/SvJ * C57BL/6J J:230887 View
schizophrenia Nrg1tm2Zhou/Nrg1+ involves: 129S4/SvJae * C57BL/6 J:81106 View
schizophrenia Tg(Eno2tTA)5030Nes/0
Tg(tetO-NRG1_i4)6Ajla/0
involves: C57BL/6 * C57BL/6J * SJL J:231737 View
schizophrenia Tg(Camk2a-ESR1/Disc1*)2698.1Sva/0 involves: C57BL/6 * C57BL/6NTac J:127235 View
schizophrenia Tg(Disc1/EGFP)M19Sshe/0 involves: C57BL/6JCrl * CBA/CaCrl J:143557 View
      schizophrenia Srgap3tm1.1Zi/Srgap3tm1.1Zi B6.129(SJL)-Srgap3tm1.1Zi J:192388 View
schizophrenia Nr4a2tm1Tpe/Nr4a2+ B6.129P2-Nr4a2tm1Tpe J:147544 View
schizophrenia Slc6a1tm1Mlit/Slc6a1tm1Mlit B6.129S1-Slc6a1tm1Mlit J:204368 View
schizophrenia Mdktm1Tmu/Mdktm1Tmu B6.129S2-Mdktm1Tmu J:151029 View
schizophrenia Chrna7tm1Bay/Chrna7tm1Bay B6.129S7-Chrna7tm1Bay/J J:214099 View
schizophrenia Relnrl/Reln+ B6.Cg-Relnrl J:223944 View
schizophrenia Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-Gnas)1593Mpke/0
B6.Cg-Tg(Camk2a-tTA)1Mmay Tg(tetO-Gnas)1593Mpke J:166114 View
schizophrenia Relnrl/Reln+ B6C3Fe a/a-Relnrl/J J:107996 View
schizophrenia Zfp521tm1Nokh/Zfp521tm1Nokh B6J.Cg-Zfp521tm1Nokh J:214267 View
schizophrenia Cplx2tm1Rmnd/Cplx2tm1Rmnd B6NCrl.Cg-Cplx2tm1Rmnd J:175056 View
schizophrenia Ppp3r1tm1Stl/Ppp3r1tm1Stl
Tg(Camk2a-cre)CW2Stl/0
C57BL/6-Ppp3r1tm1Stl Tg(Camk2a-cre)CW2Stl J:73203, J:84640 View
schizophrenia Tg(Camk2a-Magi2)1Shlee/? C57BL/6J-Tg(Camk2a-Magi2)1Shlee J:218971 View
schizophrenia Srrrgsc1872/Srrrgsc1872 C57BL/6JJcl-Srrrgsc1872 J:151337 View
schizophrenia Map6tm1Job/Map6tm1Job either: 129S2/SvPas or (involves: 129S2/SvPas * BALB/c) J:79099 View
schizophrenia YwhazGt(OST432062)Lex/YwhazGt(OST432062)Lex either: B6.129S5-YwhazGt(OST432062)Lex or C.129S5-YwhazGt(OST432062)Lex or (involves: 129S5/SvEvBrd * 129T2/SvEmsWehi)) J:217297 View
schizophrenia Nrxn1tm1Sud/Nrxn1tm1Sud involves: 129 * C57BL/6 J:153748 View
schizophrenia Plcb1tm1Hssh/Plcb1tm1Hssh involves: 129/Sv * C57BL/6 J:151070 View
schizophrenia Slc6a3tm1Mca/Slc6a3tm1Mca involves: 129P2/OlaHsd J:31328 View
schizophrenia Ppm1gtm1Dgen/Ppm1g+ involves: 129P2/OlaHsd * C57BL/6 J:101679 View
schizophrenia Avpr1atm1Dgen/Avpr1atm1Dgen involves: 129P2/OlaHsd * C57BL/6 J:101679 View
schizophrenia Chst3tm1Dgen/Chst3tm1Dgen involves: 129P2/OlaHsd * C57BL/6 J:101679 View
schizophrenia Ctsctm1Dgen/Ctsctm1Dgen involves: 129P2/OlaHsd * C57BL/6 J:101679 View
schizophrenia Grin1tm1Bhk/Grin1tm1Bhk involves: 129P2/OlaHsd * C57BL/6 * DBA/2 J:57125 View
schizophrenia Map2k7tm1Pngr/Map2k7+ involves: 129P2/OlaHsd * C57BL/6J J:188339 View
schizophrenia Ncstntm1.1Sud/Ncstntm1.1Sud
Olig1tm1(cre)Rth/Olig1+
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ J:234705 View
schizophrenia Srrtm1.2Jtc/Srrtm1.2Jtc involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 J:158266 View
schizophrenia Sp4tm3Krc/Sp4tm3Krc involves: 129S1/Sv * 129X1/SvJ * Black Swiss J:163637 View
schizophrenia Bace1tm1Pcw/Bace1tm1Pcw involves: 129S1/Sv * 129X1/SvJ * C57BL/6J J:133643 View
schizophrenia Taar1tm1Tdw/Taar1tm1Tdw involves: 129S1/Sv * C57BL/6J J:141501 View
schizophrenia Map6tm1Job/Map6tm1Job involves: 129S2/SvPas * C57BL/6 J:225083 View
schizophrenia Map6tm1Job/Map6+ involves: 129S2/SvPas * C57BL/6 J:225083 View
schizophrenia Zic2tm1Jaru/Zic2+ involves: 129S4/SvJae * C57BL/6J J:174352 View
schizophrenia Csmd1tm1Lex/Csmd1tm1Lex involves: 129S5/SvEvBrd * C57BL/6NTac J:209700 View
schizophrenia Syngap1tm1Rlh/Syngap1+ involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J J:194146 View
schizophrenia Snap25Bdr/Snap25+ involves: BALB/cAnNCrl J:119733 View
schizophrenia ckr/ckr involves: C3H/HeRos * C57BL/10Ros J:87399 View
schizophrenia Lrrtm1tm1.1Jaru/Lrrtm1tm1.1Jaru involves: C57BL/6 * C57BL/6J J:174350 View
schizophrenia Tg(Thy1-Tcf4)1Mjro/0 involves: C57BL/6N * FVB/N J:197081 View
Transgenes and
Other Mutations
     schizophrenia Del(16Dgcr2-Hira)3Aam/+ involves: 129S7/SvEvBrd * C57BL/6J J:158957 View
schizophrenia Tg(GFAP-tTA)#Hyms/0
Tg(tetO-HMOX1)#Hyms/0
involves: FVB J:186620 View
Additional Complex Models     schizophrenia Pdgfrbtm1Msas/Pdgfrbtm1Msas
Tg(Nes-cre)1Nogu/0
B6J.Cg-Pdgfrbtm1Msas Tg(Nes-cre)1Nogu J:229179 View
Disease phenotype
not observed
No similarity to the expected human disease phenotype was found.

        Allelic Composition Genetic Background Reference Phenotypes
NOT Models     schizophrenia Csmd1tm1Lex/Csmd1tm1Lex B6;129S5-Csmd1tm1Lex/Mmucd J:194991 View
schizophrenia Rtn4rrgsc1836/Rtn4rrgsc1836 C57BL/6JJcl-Rtn4rrgsc1836 J:176996 View
schizophrenia Rtn4rtm1Gogo/Rtn4rtm1Gogo involves: 129 * C57BL/6J J:130368 View

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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory