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Mouse Models of combined T cell and B cell immunodeficiency
Mouse Models All mouse models of combined T cell and B cell immunodeficiency (Disease Ontology ID: DOID:628)

        Allelic Composition Genetic Background Reference Phenotypes
      adenosine deaminase deficiency Adatm1Mw/Adatm1Mw
Tg(PLADA)4118Rkmb/0
involves: 129S7/SvEvBrd * C57BL/6 J:73418 View
DNA ligase IV deficiency Lig4tiny/Lig4tiny C57BL/6-Lig4tiny J:122725 View
DNA ligase IV deficiency Lig4tm2.1Fwa/Lig4tm2.1Fwa involves: 129S6/SvEvTac J:157574 View
MHC class II deficiency Ciitatm2Wrth/Ciitatm2Wrth involves: 129P2/OlaHsd * C57BL/6 J:92170 View
MHC class II deficiency Ciitatm1Ccum/Ciitatm1Ccum involves: 129S2/SvPas * C57BL/6J J:31601 View
Omenn syndrome Rag2tm1Avla/Rag2tm1Avla involves: 129/Sv * C57BL/6 J:122108 View
purine nucleoside phosphorylase deficiency Pnpe/Pnpe C57BL/6J-Pnpe J:39328 View
purine nucleoside phosphorylase deficiency Pnpf/Pnpf C57BL/6J-Pnpf J:39328 View
purine nucleoside phosphorylase deficiency Pnpe/Pnpe involves: C3H/HeHa * C57BL/6J J:23354 View
purine nucleoside phosphorylase deficiency Pnpf/Pnpf involves: C3H/HeHa * C57BL/6J J:23354 View
purine nucleoside phosphorylase deficiency Pnpg/Pnpg involves: C57BL/6 * DBA/2J J:39328 View
T-cell immunodeficiency, congenital alopecia, and nail dystrophy Foxn1nu-Y/Foxn1nu-Y 101/HY-Foxn1nu-Y J:29022 View
T-cell immunodeficiency, congenital alopecia, and nail dystrophy Foxn1nu-2J/Foxn1nu-2J B6(SJL)-Foxn1nu-2J/GrsrJ J:222308 View
T-cell immunodeficiency, congenital alopecia, and nail dystrophy Foxn1tm1Tbo/Foxn1tm1Tbo involves: 129S1/Sv J:33796 View
T-cell immunodeficiency, congenital alopecia, and nail dystrophy Foxn1nu/Foxn1nu Not Specified J:11959 View
Disease phenotype
not observed
No similarity to the expected human disease phenotype was found.

        Allelic Composition Genetic Background Reference Phenotypes
NOT Models     combined T cell and B cell immunodeficiency Il2rgtm1Sug/Y either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129S6/SvEvTac * C57BL/6) J:31167 View
combined T cell and B cell immunodeficiency Il2rgtm1Cgn/Il2rgtm1Cgn involves: 129 * CB20 J:22521 View
combined T cell and B cell immunodeficiency Il2rgtm1Cgn/Y involves: 129 * CB20 J:22521 View
gamma chain deficiency Il2rgtm1Sug/Y either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129S6/SvEvTac * C57BL/6) J:31167 View
gamma chain deficiency Il2rgtm1Cgn/Il2rgtm1Cgn involves: 129 * CB20 J:22521 View
gamma chain deficiency Il2rgtm1Cgn/Y involves: 129 * CB20 J:22521 View
Omenn syndrome Rag1tm1Jsek/Rag1tm1Jsek involves: 129S6/SvEvTac J:146912 View

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/14/2017
MGI 6.08
The Jackson Laboratory