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Mouse Models of neural tube defect
Mouse Models All mouse models of neural tube defect (Disease Ontology ID: DOID:0080074)

        Allelic Composition Genetic Background Reference Phenotypes
      neural tube defect Celsr1Crsh/Celsr1+
Vangl2Lp/Vangl2+
C3H.Cg-Vangl2Lp Celsr1Crsh J:216413 View
neural tube defect ScribCrc/Scrib+
Vangl2Lp/Vangl2+
C3H.Cg-Vangl2Lp ScribCrc J:216413 View
neural tube defect Vangl1Gt(XL802)Byg/Vangl1+
Vangl2Lp/Vangl2+
involves: 129P2/OlaHsd * C57BL/6J * LPT/LeJ J:132697 View
neural tube defect Mthfrtm1Rzn/Mthfrtm1Rzn involves: 129S1/Sv * 129X1/SvJ * BALB/c J:67779 View
neural tube defect Vangl2Lp/Vangl2Lp involves: CBA/Ca * LPT/Le J:47700 View
parietal foramina Alx4Lst-2J/Alx4Lst-2J C57BL/6J-Alx4Lst-2J/J J:223288 View
parietal foramina Msx2tm1Rilm/Msx2tm1Rilm either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6J) J:61509 View
      neural tube defect Lrp6Cd/Lrp6Cd A-Lrp6Cd J:58433, J:101423 View
neural tube defect Pax3Sp-1Wli/Pax3Sp-1Wli involves: C57BL/6J * CBA/CaJ J:196572 View
neural tube defect Mthfd1ltm1b(EUCOMM)Wtsi/Mthfd1ltm1b(EUCOMM)Wtsi involves: C57BL/6N * FVB/N J:193285 View
Additional Complex Models     neural tube defect Celsr1Crsh/Celsr1+
ScribCrc/Scrib+
C3H.Cg-ScribCrc Celsr1Crsh J:216413 View
neural tube defect Celsr1Scy/Celsr1+
ScribCrc/Scrib+
C3H.Cg-ScribCrc Celsr1Scy J:216413 View
neural tube defect Pax1un/Pax1+
Tcf3tm1Cmu/Tcf3tm1Cmu
involves: 129P2/OlaHsd * C3H * C57BL/6 J:103567 View
Disease phenotype
not observed
No similarity to the expected human disease phenotype was found.

        Allelic Composition Genetic Background Reference Phenotypes
NOT Models     neural tube defect Vangl1Gt(XL802)Byg/Vangl1Gt(XL802)Byg involves: 129P2/OlaHsd * C57BL/6J J:132697 View

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory