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Mouse Models of Hutchinson-Gilford Progeria Syndrome; HGPS
Mouse Models All mouse models of Hutchinson-Gilford Progeria Syndrome; HGPS (OMIM ID: 176670)

        Allelic Composition Genetic Background Reference Phenotypes
      Lmnatm2Stw/Lmnatm2Stw involves: 129S1/Sv J:83382 View
Lmnatm1.1Otin/Lmnatm1.1Otin involves: 129P2/OlaHsd * C57BL/6 J:177575, J:177632, J:211388 View
Lmnatm1Lgf/Lmna+ involves: 129P2/OlaHsd * C57BL/6 J:113119 View
LmnaDhe/Lmna+ B6(D2)-LmnaDhe/TyGrsrJ J:171665 View
Lmnatm1.1Otin/Lmna+ involves: 129P2/OlaHsd * C57BL/6 J:211388 View
      Zmpste24tm1Sgy/Zmpste24tm1Sgy B6.129S4-Zmpste24tm1Sgy J:106706 View
Zmpste24tm1Otin/Zmpste24tm1Otin involves: 129P2/OlaHsd J:164373 View
Zmpste24tm1Sgy/Zmpste24tm1Sgy involves: 129S4/SvJae * C57BL/6 J:95274 View
Transgenes and
Other Mutations
     Tg(LMNA*G608G)HClns/? C57BL/6-Tg(LMNA*G608G)HClns/J J:107176 View
Additional Complex Models     Tg(KRT5-tTA)1216Glk/0
Tg(tetO-LMNA*G608G,-EGFP)VF1-07Maer/0
involves: FVB/N J:145312 View
Disease phenotype
not observed
No similarity to the expected human disease phenotype was found.

        Allelic Composition Genetic Background Reference Phenotypes
NOT Models     Lmnatm5Lgf/Lmnatm5Lgf involves: 129P2/OlaHsd * C57BL/6 J:160705 View
Lmnatm8Lgf/Lmnatm8Lgf involves: 129P2/OlaHsd J:167229 View

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory