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Mouse Models of Noonan Syndrome 1; NS1
Mouse Models All mouse models of Noonan Syndrome 1; NS1 (OMIM ID: 163950)

        Allelic Composition Genetic Background Reference Phenotypes
      Ptpn11tm1Bgn/Ptpn11+ involves: 129S4/SvJae * C57BL/6J J:91609 View
Transgenes and
Other Mutations
     Tg(CAG-cat,-Ptpn11*Q97R)1Rbns/0
Tg(Tek-cre)12Flv/0
involves: C3H * C57BL/6 * FVB/N J:142212 View
Tg(CAG-cat,-Ptpn11*Q97R)1Rbns/0
Tg(Wnt1-cre)11Rth/0
involves: C57BL/6J * CBA/J * FVB/N J:153094 View
Tg(Myh7-Ptpn11*Q79R)11Rbns/0 FVB.Cg-Tg(Myh7-Ptpn11*Q79R)11Rbns J:123963 View
Disease phenotype
not observed
No similarity to the expected human disease phenotype was found.

        Allelic Composition Genetic Background Reference Phenotypes
NOT Models     Ptpn11tm1Rbn/Ptpn11tm1Rbn involves: 129 * Black Swiss J:35137 View
Ptpn11tm1Paw/Ptpn11tm1Paw involves: 129S1/Sv * 129X1/SvJ * CD-1 J:43740 View
Ptpn11tm1Rbn/Ptpn11+ involves: 129 * Black Swiss J:35137 View

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory