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Mouse Models of Neurofibromatosis, Type I; NF1
Mouse Models All mouse models of Neurofibromatosis, Type I; NF1 (OMIM ID: 162200)

        Allelic Composition Genetic Background Reference Phenotypes
      Nf1tm1Fcr/Nf1tm1Fcr either: (involves: 129S/SvEv) or (involves: 129S/SvEv * C57BL/6J) J:18048 View
Nf1tm1Cbr/Nf1tm1Cbr involves: 129S1/Sv * C57BL/6 J:68489 View
Nf1tm1Par/Nf1tm1Par
Tg(Mpz-cre)94Imeg/0
involves: 129S1/Sv * 129X1/SvJ J:80323 View
Nf1tm1Par/Nf1tm1Fcr
Tg(GFAP-cre)#Gtm/0
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA J:165209 View
Nf1tm1Par/Nf1tm1Par
Tg(Fabp7-cre)2Gtm/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA J:138868 View
Nf1tm1Tyj/Nf1+ involves: 129S2/SvPas * C57BL/6J J:38703 View
Nf1tm1Par/Nf1tm1Par
Tg(Pax3-cre)1Joe/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL J:80323 View
Nf1tm1Par/Nf1tm1Par
Tg(Syn1-cre)671Jxm/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA J:68558 View
Nf1tm1Par/Nf1tm1Par
Tg(Prrx1-cre)1Cjt/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * C57BL/6N * SJL/J J:193350 View
Grin1tm1Stl/Grin1+
Nf1tm1Tyj/Nf1+
involves: 129S2/SvPas * C57BL/6J J:38703 View
Nf1tm1Par/Nf1tm1Par
Tg(Prrx1-cre)1Cjt/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J J:173779 View
Nf1tm1Tyj/Nf1+
Trp53tm1Brd/Trp53+
involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6 J:58877 View
Nf1tm1Tyj/Nf1+
Trp53tm1Tyj/Trp53+
involves: 129/Sv * C57BL/6 J:58876 View
Nf1tm1Par/Nf1tm1Par
Tg(Wnt1-cre)11Rth/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA J:80323 View
      Krastm4Tyj/Kras+
Ptentm1Hwu/Pten+
Tg(Gfap-cre)77.6Mvs/0
involves: 129S4/SvJae * BALB/c * C57BL/6NHsd J:154673 View
Disease phenotype
not observed
No similarity to the expected human disease phenotype was found.

        Allelic Composition Genetic Background Reference Phenotypes
NOT Models     Nf1tm1Tyj/Nf1+ involves: 129S2/SvPas * C57BL/6 J:18542 View

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory