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Mouse Models of holoprosencephaly
Mouse Models All mouse models of holoprosencephaly (Disease Ontology ID: DOID:4621)

        Allelic Composition Genetic Background Reference Phenotypes
      holoprosencephaly Zic2Ku/Zic2Ku 129S.CAnNCrl(C3)-Zic2Ku J:238567 View
holoprosencephaly Boctm1Rsk/Boctm1Rsk
Cdontm1Rsk/Cdontm1Rsk
B6.129-Boctm1Rsk Cdontm1Rsk J:171767 View
holoprosencephaly Boctm2Rsk/Boctm2Rsk
Cdontm1Rsk/Cdontm1Rsk
B6.129-Boctm2Rsk Cdontm1Rsk J:171767 View
holoprosencephaly Zic2Ku/Zic2Ku C3.CAnNCrl-Zic2Ku J:138862 View
holoprosencephaly Boctm1Rsk/Boctm1Rsk
Cdontm1Rsk/Cdontm1Rsk
involves: 129/Sv * 129S6/SvEvTac J:171767 View
holoprosencephaly Boctm1Rsk/Boc+
Cdontm1Rsk/Cdontm1Rsk
involves: 129/Sv * 129S6/SvEvTac J:171767 View
holoprosencephaly Boctm2Rsk/Boctm2Rsk
Cdontm1Rsk/Cdontm1Rsk
involves: 129/Sv * 129S6/SvEvTac J:171767 View
holoprosencephaly Boctm2Rsk/Boc+
Cdontm1Rsk/Cdontm1Rsk
involves: 129/Sv * 129S6/SvEvTac J:171767 View
holoprosencephaly Cdontm1Rsk/Cdontm1Rsk involves: 129/Sv * C57BL/6 J:82221 View
holoprosencephaly Cdontm2Rsk/Cdontm2Rsk involves: 129/Sv * C57BL/6 J:82221 View
holoprosencephaly Six3tm1Gco/Six3tm1Gco involves: 129S1/Sv J:81797 View
holoprosencephaly Shhtm1Chg/Shhtm1Chg involves: 129S1/Sv * 129X1/SvJ J:35802 View
holoprosencephaly Six3tm3.1Gco/Six3+
Shhtm1Chg/Shh+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:140315 View
holoprosencephaly Six3tm3Gco/Six3tm3Gco
Foxg1tm1(cre)Skm/Foxg1+
involves: 129S1/Sv * C57BL/6 J:140315 View
holoprosencephaly Six3tm4(cre/ERT2)Gco/Six3+ involves: 129S1/Sv * C57BL/6 J:140315 View
holoprosencephaly Zic2tm1Jaru/Zic2tm1Jaru involves: 129S4/SvJae * C57BL/6 J:60644 View
holoprosencephaly Disp1icb/Disp1tm1Amc
Shhtm1Amc/Shh+
involves: 129X1/SvJ * C57BL/6J J:92058 View
holoprosencephaly Shhtm1Chg/Shhtm1Chg involves: C57BL/6 J:89364 View
Disease phenotype
not observed
No similarity to the expected human disease phenotype was found.

        Allelic Composition Genetic Background Reference Phenotypes
NOT Models     holoprosencephaly Tgif1tm1.1Caw/Tgif1tm1.1Caw involves: C57BL/6 * FVB/N J:97642 View

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last database update
03/14/2017
MGI 6.08
The Jackson Laboratory