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Mouse Models of Huntington Disease; HD
Mouse Models All mouse models of Huntington Disease; HD (OMIM ID: 143100)

        Allelic Composition Genetic Background Reference Phenotypes
      Htttm1Mfc/Htttm1Mfc involves: 129S1/Sv * C57BL/6 J:85298, J:141673 View
Htttm2Detl/Htttm2Detl involves: 129P2/OlaHsd * C57BL/6J J:123681 View
Htttm1Detl/Htttm1Detl involves: 129P2/OlaHsd * C57BL/6J J:67074 View
Htttm4Mem/Htttm4Mem involves: 129S1/Sv * 129X1/SvJ * CD-1 J:60937, J:99425, J:111237 View
Htttm5Mem/Htttm5Mem involves: 129S1/Sv * 129X1/SvJ * CD-1 J:60937, J:99425, J:111237 View
Htttm1.1Pfs/Htt+ involves: 129S4/SvJae * C57BL/6 J:54906 View
Htttm2.1Pfs/Htt+ involves: 129X1/SvJ * C57BL/6 J:54906 View
Htttm2Msl/Htttm2Msl involves: 129S1/Sv * C57BL/6J J:76018, J:79137 View
Htttm1.1Tna/Htttm1.1Tna involves: 129P2/OlaHsd * C57BL/6J J:76017 View
Htttm1Detl/Htt+ involves: 129P2/OlaHsd * C57BL/6J J:67074 View
Htttm1Hay/Htt+ involves: C57BL/6J J:25941 View
Htttm1Szi/Htttm2Szi
Tg(Camk2a-cre)2Szi/0
involves: 129S/SvEv * 129S1/Sv * C57BL/6 * CBA J:65520 View
Htttm4Mem/Htt+ involves: 129S1/Sv * 129X1/SvJ * CD-1 J:60937 View
Htttm1.1Tna/Htt+ involves: 129P2/OlaHsd * C57BL/6J J:76017 View
Htttm1Szi/Htttm2Szi
Tg(Camk2a-cre)1Szi/0
involves: 129S/SvEv * 129S1/Sv * C57BL/6 * CBA J:65520 View
Htttm5Mem/Htt+ involves: 129S1/Sv * 129X1/SvJ * CD-1 J:60937 View
      Drd1atm2Jcd/Drd1a+
Tg(Camk2a-cre)2Gsc/0
involves: 129S4/SvJae * FVB/N J:120070 View
Zdhhc13Gt(AC0492)Wtsi/Zdhhc13Gt(AC0492)Wtsi FVB.129P2-Zdhhc13Gt(AC0492)Wtsi J:191129 View
Zdhhc17Gt(RRJ233)Byg/Zdhhc17Gt(RRJ233)Byg FVB.129P2-Zdhhc17Gt(RRJ233)Byg J:175800 View
Transgenes and
Other Mutations
     Tg(CMV-HTT*48Q)BTag/Tg(CMV-HTT*48Q)BTag involves: FVB/N J:50173 View
Tg(CMV-HTT*48Q)BTag/0 involves: FVB/N J:50173 View
Tg(CMV-HTT*89Q)ATag/Tg(CMV-HTT*89Q)ATag involves: FVB/N J:50173 View
Tg(CMV-HTT*89Q)ATag/0 involves: FVB/N J:50173 View
Tg(GFAP-HTT*160Q)1Xjl/0 either: (involves: FVB/NCrl) or (involves: C3H * C57BL/6 * FVB/NCrl) J:156460 View
Tg(GFAP-HTT*160Q)31Xjl/0 either: (involves: FVB/NCrl) or (involves: C3H * C57BL/6 * FVB/NCrl) J:156460 View
Tg(HD82Gln)81Gschi/0 involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 * CD-1 J:172874 View
Tg(HD82Gln)81Gschi/0 involves: C3H/HeJ * C57BL/6 J:53797 View
Cnr1tm1Map/Cnr1tm1Map
Tg(HD82Gln)81Gschi/0
involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 * CD-1 J:172874 View
Tg(HD)63Aron/? involves: C57BL/6 * SJL J:72772 View
Tg(HDexon1)61Gpb/? involves: C57BL/6 * CBA J:42085, J:203027 View
Tg(HDexon1)62Gpb/0 B6CBA-Tg(HDexon1)62Gpb/1J J:99425, J:111237 View
Tg(HDexon1)62Gpb/0 involves: C57BL/6 * CBA J:42085 View
Tg(HDexon1)62Gpb/0 involves: C57BL/6J * CBA/J J:36689 View
Tg(HTT*97Q)IXwy/0 FVB-Tg(HTT*97Q)IXwy J:137345 View
Tg(HTT*)1Xwy/0 FVB-Tg(HTT*)1Xwy J:157723 View
Tg(HTT*/EGFP)150Nn/0 involves: C57BL/6 * DBA/2 J:174269 View
Tg(HTT*/EGFP)190Nn/0 involves: C57BL/6 * DBA/2 J:174269 View
Tg(Ppp1r1b-HTT*)1Meeh/0 C57BL/6J-Tg(Ppp1r1b-HTT*)1Meeh J:139807 View
Tg(Prnp-HTT*82Q)52Caro/0 involves: C3H * C57BL/6 J:179364 View
Tg(Prnp-HTT*82Q,KRT14-EGFP)C63Dbo/0 Not Specified J:173756 View
Tg(Prnp-SNAP25/HTT*150Q)8Xjl/0 involves: FVB J:201806 View
Tg(UBC-GFP/HTT*84Q)22Shya/0 involves: FVB J:209055 View
Tg(YAC72)2511Hay/Tg(YAC72)2511Hay FVB/N-Tg(YAC72)2511Hay J:105728 View
Tg(YAC72)2511Hay/? involves: FVB/N J:55405 View
Tg(YAC128)53Hay/0 FVB/N-Tg(YAC128)53Hay J:84453, J:105723, J:111237 View
Tg(YAC128)55Hay/Tg(YAC128)55Hay FVB/N-Tg(YAC128)55Hay J:105723, J:105728 View
Tg(YAC128)55Hay/0 FVB/N-Tg(YAC128)55Hay J:105723 View
Tg(YAC128)#Hay/0 FVB/N-Tg(YAC128)#Hay J:98736 View
Additional Complex Models     Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-HTT*94Q,-lacZ)1Rhn/0
involves: C57BL/6 * CBA J:61490 View
Gt(ROSA)26Sortm1(HD*103Q)Xwy/?
Tg(Nes-cre)1Kln/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL J:99759 View
Disease phenotype
not observed
No similarity to the expected human disease phenotype was found.

        Allelic Composition Genetic Background Reference Phenotypes
NOT Models     Htttm1Szi/Htttm1Szi either: (involves: 129/Sv * C57BL/6J) or (involves: 129/Sv * MF1) J:29267 View
Htttm1Mem/Htttm1Mem involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 J:27183 View
Htttm1Hay/Htttm1Hay involves: C57BL/6J J:25941 View
Htttm7Mem/Htttm7Mem involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * CD-1 J:44391 View
Htttm3Mem/Htttm3Mem involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * CD-1 J:44391 View
Htttm2Mem/Htttm2Mem involves: 129S1/Sv * 129X1/SvJ * CD-1 J:99425 View
Htttm3Mem/Htttm3Mem involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:99425 View
Htttm6Mem/Htttm8Mem involves: 129S1/Sv * 129X1/SvJ * Swiss Webster J:72915 View
Htttm1Mem/Htttm7Mem involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * CD-1 J:44391 View
Emx1tm1(cre)Ito/?
Gt(ROSA)26Sortm1(HD*103Q)Xwy/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL J:99759 View
Hap1tm1Hay/Hap1tm1Hay involves: 129S1/Sv * 129X1/SvJ * ICR J:76174 View
Hap1tm1Xjl/Hap1tm1Xjl involves: 129S6/SvEvTac * Black Swiss J:84682 View

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory