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Mouse Models of Emphysema, Hereditary Pulmonary
Mouse Models All mouse models of Emphysema, Hereditary Pulmonary (OMIM ID: 130700)

        Allelic Composition Genetic Background Reference Phenotypes
      Bloc1s6pa/Bloc1s6pa B6.Cg-Bloc1s6pa/J J:4098 View
Fbn1Tsk/Fbn1+
Il4ratm1Sz/Il4ratm1Sz
involves: BALB/cJ * C57BL/6J * C57BL/10 * DBA/2 J:68448 View
Fbn1Tsk/Fbn1+
Tgfb1tm1N/Tgfb1+
involves: 129S/SvEv * C57BL/6J * C57BL/10 * DBA/2 J:68448 View
Fbn1Tsk/Fbn1+ B6.Cg-Fbn1Tsk J:30961, J:6566, J:15018, J:1326, J:68448 View
Fbn1Tsk/Fbn1+
Il4ratm1Sz/Il4ra+
involves: BALB/cJ * C57BL/6J * C57BL/10 * DBA/2 J:68448 View
Fut8tm1Nta/Fut8tm1Nta involves: 129S2/SvPas J:102932 View
Itgb6tm1Des/Itgb6tm1Des involves: 129T2/SvEms J:89578 View
Juntm4Wag/Juntm4Wag
Tg(Sftpc-cre)1Blh/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 J:179883 View
Klkl/Klkl either: C.Cg-Klkl or (involves: C3H/J * C57BL/6J) J:44109 View
Tlr4tm1Aki/Tlr4tm1Aki B6.129P2-Tlr4tm1Aki J:114985 View
Transgenes and
Other Mutations
     Tg(HP-MMP1a)34-1Cha/Tg(HP-MMP1a)34-1Cha involves: C57BL/6J * CBA/J J:164058 View
Tg(HP-MMP1a)34-1Cha/0 involves: C57BL/6J * CBA/J J:164058 View
Tg(Msr1-MMP9)#Apar/0 B6.Cg-Tg(Msr1-MMP9)#Apar J:136830 View
Additional Complex Models     Tg(SFTPC-rtTA)5Jaw/0
Tg(tetO-PLAGL2)P3Ysy/0
involves: FVB/N J:152422 View
Disease phenotype
not observed
No similarity to the expected human disease phenotype was found.

        Allelic Composition Genetic Background Reference Phenotypes
NOT Models     Itgb6tm1Des/Itgb6tm1Des
Mmp12tm1Sds/Mmp12tm1Sds
involves: 129/Sv * 129T2/SvEms J:89578 View

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory