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Mouse Models of Cerebral Arteriopathy, Autosomal Dominant, with Subcortical Infarcts and Leukoencephalopathy; CADASIL
Mouse Models All mouse models of Cerebral Arteriopathy, Autosomal Dominant, with Subcortical Infarcts and Leukoencephalopathy; CADASIL (OMIM ID: 125310)

        Allelic Composition Genetic Background Reference Phenotypes
      Notch3tm1.1Dwr/Notch3tm1.1Dwr involves: 129S/SvEv * Swiss J:191454 View
Notch3tm1.1Dwr/Notch3+ involves: 129S/SvEv * Swiss J:191454 View
Gt(ROSA)26Sortm3(NOTCH3*R1031C)Sat/Gt(ROSA)26Sor+
Notch3Gt(PST033)Byg/Notch3Gt(PST033)Byg
Tg(Tagln-cre)1Her/0
involves: 129 * C57BL/6 * SJL J:171887 View
Gt(ROSA)26Sortm2(NOTCH3*C455R)Sat/Gt(ROSA)26Sor+
Notch3Gt(PST033)Byg/Notch3Gt(PST033)Byg
Tg(Tagln-cre)1Her/0
involves: 129 * C57BL/6 * SJL J:171887 View
Additional Complex Models     Gt(ROSA)26Sortm3(NOTCH3*R1031C)Sat/Gt(ROSA)26Sor+
Tg(Tagln-cre)1Her/0
involves: 129S2/SvEv * 129S6/SvEvTac * C57BL/6 * SJL J:171887 View
Disease phenotype
not observed
No similarity to the expected human disease phenotype was found.

        Allelic Composition Genetic Background Reference Phenotypes
NOT Models     Notch3tm1Ul/Notch3tm1Ul Not Specified J:95927 View
Notch3tm1Ul/Notch3+ Not Specified J:95927 View

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory