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Mouse Models of hypersensitivity reaction type II disease
Mouse Models All mouse models of hypersensitivity reaction type II disease (Disease Ontology ID: DOID:417)

        Allelic Composition Genetic Background Reference Phenotypes
      autoimmune polyendocrine syndrome type 1 Airetm1.1Doi/Airetm1.1Doi B6.129S2-Airetm1.1Doi/Doi J:107432 View
autoimmune polyendocrine syndrome type 1 Airetm1Mmat/Airetm1Mmat B6.Cg-Airetm1Mmat J:96580 View
autoimmune polyendocrine syndrome type 1 Airetm1.1Doi/Airetm1.1Doi C.129S2-Airetm1.1Doi/Doi J:107432 View
autoimmune polyendocrine syndrome type 1 Airetm1Mmat/Airetm1Mmat C.Cg-Airetm1Mmat J:96580 View
autoimmune polyendocrine syndrome type 1 Airetm1.1Doi/Airetm1.1Doi involves: 129S2/SvPas * C57BL/6 J:83422 View
autoimmune polyendocrine syndrome type 1 Airetm1Pltn/Airetm1Pltn involves: 129S4/SvJae * C57BL/6 J:77873 View
autoimmune polyendocrine syndrome type 1 Airetm1Mmat/Airetm1Mmat involves: C57BL/6 * CBA J:96580 View
autoimmune polyendocrine syndrome type 1 Airetm1.1Doi/Airetm1.1Doi NOD.129S2(B6)-Airetm1.1Doi/Doi J:107432 View
autoimmune polyendocrine syndrome type 1 Airetm1.1Doi/Airetm1.1Doi SJL.129S2-Airetm1.1Doi/Doi J:107432 View
familial Mediterranean fever Mefvtm3.1(MEFV)Chae/Mefvtm3.1(MEFV)Chae B6.129S6-Mefvtm3.1(MEFV)Chae J:172117 View
familial Mediterranean fever Mefvtm4.1(MEFV)Chae/Mefvtm4.1(MEFV)Chae B6.129S6-Mefvtm4.1(MEFV)Chae J:172117 View
familial Mediterranean fever Mefvtm5.1(MEFV)Chae/Mefvtm5.1(MEFV)Chae B6.129S6-Mefvtm5.1(MEFV)Chae J:172117 View
familial Mediterranean fever Mefvtm1Chae/Mefvtm1Chae either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * C57BL/6) J:82763 View
systemic lupus erythematosus Fcgr2btm1Ttk/Fcgr2btm1Ttk B6.129S4-Fcgr2btm1Ttk J:64152 View
systemic lupus erythematosus Fcgr2btm1Ttk/Fcgr2btm1Ttk
Traf3ip2tm1Sbn/Traf3ip2+
involves: 129 * 129S4/SvJae * C57BL/6 J:191090 View
systemic lupus erythematosus Dnase1tm1Tmo/Dnase1tm1Tmo involves: 129P2/OlaHsd * C57BL/6 J:62549 View
      autoimmune hemolytic anemia Tg(KRT5-rtTA)1Glk/0
Tg(tetO/CMV-Tslp)#Sfz/0
C.Cg-Tg(KRT5-rtTA)1Glk Tg(tetO/CMV-Tslp)#Sfz J:182756 View
Guillain-Barre syndrome Airetm1Mand/Aire+ NOD.129P2-Airetm1Mand J:188686 View
Guillain-Barre syndrome Cd86tm1Shr/Cd86tm1Shr NOD.129S4-Cd86tm1Shr J:71352, J:142046 View
hypersensitivity reaction type II disease Cd200tm1Jods/Cd200tm1Jods C57BL/6-Cd200tm1Jods J:65982 View
hypersensitivity reaction type II disease Gpr132tm1Witt/Gpr132tm1Witt involves: 129X1/SvJ * BALB/c J:69473 View
primary biliary cirrhosis Map3k14aly/Map3k14aly involves: C57BL/6J J:48224 View
Sjogren's syndrome Ccr7tm1Rfor/Ccr7tm1Rfor B6.129P2-Ccr7tm1Rfor J:110910 View
Sjogren's syndrome Tg(Tnfsf13b)1Fma/0 B6.Cg-Tg(Tnfsf13b)1Fma J:73711 View
Sjogren's syndrome Faslpr/Faslpr C3.MRL-Faslpr J:1028 View
Sjogren's syndrome Traf3ip2tm1.1Lix/Traf3ip2tm1.1Lix C.129-Traf3ip2tm1.1Lix J:138560 View
Sjogren's syndrome plt/plt either: B6.DDD-plt or C.DDD-plt J:110910 View
Sjogren's syndrome St14tm2Bug/St14tm3Bug
Tg(MMTV-cre)4Mam/0
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J * FVB/NJ * N:Black Swiss J:213072 View
Sjogren's syndrome Airetm1.1Doi/Airetm1.1Doi
Il1r1tm1Imx/Il1r1tm1Imx
involves: 129S2/SvPas * 129S7/SvEvBrd * NOD J:163691 View
Sjogren's syndrome Airetm1.1Doi/Airetm1.1Doi
Il1r1tm1Imx/Il1r1+
involves: 129S2/SvPas * 129S7/SvEvBrd * NOD J:163691 View
Sjogren's syndrome Thbs1tm1Hyn/Thbs1tm1Hyn involves: 129S2/SvPas * C57BL/6 J:153126 View
Sjogren's syndrome Tgfb1tm1Doe/Tgfb1tm1Doe involves: 129S2/SvPas * CF1 J:2892 View
Sjogren's syndrome Id3tm1Zhu/Id3tm1Zhu involves: 129S4/SvJaeSor J:93916 View
Sjogren's syndrome Cyp19a1tm1Esi/Cyp19a1tm1Esi involves: 129S6/SvEvTac * C57BL/6 J:92438 View
Sjogren's syndrome Id3tm2.1Zhu/Id3tm2.1Zhu
Tg(Lck-cre)#Zhu/0
involves: 129S6/SvEvTac * C57BL/6 * SJL * SJL/J J:172701 View
Sjogren's syndrome Cyp19a1tm1Sih/Cyp19a1tm1Sih involves: 129S/SvEv J:216958 View
Sjogren's syndrome Nfkbiatm1.1Pjc/Nfkbiatm1.1Pjc involves: C57BL/6 J:163686 View
Sjogren's syndrome Tg(CD2-Rorc)#Staka/0 involves: C57BL/6 J:230700 View
Sjogren's syndrome Airetm1Mmat/Airetm1Mmat involves: C57BL/6 * CBA J:96580 View
Sjogren's syndrome Map3k14aly/Map3k14aly involves: C57BL/6J J:38580 View
Sjogren's syndrome Faslpr/Faslpr
Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
MRL.Cg-Tnfrsf9tm1Byk Faslpr J:120559 View
Sjogren's syndrome Faslpr/Faslpr MRL/Mp-Faslpr J:1028, J:18512, J:21965 View
Sjogren's syndrome Faslpr/Faslpr MRL/MpJ-Faslpr/J J:123192 View
Sjogren's syndrome Muc19sld/Muc19sld NFS/N-Muc19sld J:20364, J:62145, J:106272, J:216958 View
Sjogren's syndrome Il4tm1Cgn/Il4tm1Cgn NOD.129P2-Il4tm1Cgn J:105803 View
Sjogren's syndrome E2f1tm1Meg/E2f1tm1Meg NOD.Cg-E2f1tm1Meg J:93708 View
Sjogren's syndrome Il4tm1Cgn/Il4tm1Cgn NOD.Cg-H2b Il4tm1Cgn J:105803 View
systemic lupus erythematosus Traf3ip2tm1.1Lix/Traf3ip2tm1.1Lix B6.129-Traf3ip2tm1.1Lix J:187766 View
systemic lupus erythematosus Trove2tm1Woln/Trove2tm1Woln B6.129S1-Trove2tm1Woln J:84627 View
systemic lupus erythematosus Pdcd1tm1Hon/Pdcd1tm1Hon B6.129S2-Pdcd1tm1Hon J:78802 View
systemic lupus erythematosus Ptpn22tm2Achn/Ptpn22tm2Achn
Ptprctm1Weis/Ptprctm1Weis
B6.Cg-Ptprctm1Weis Ptpn22tm2Achn J:147129 View
systemic lupus erythematosus Rassf5tm1Kina/Rassf5tm1Kina B6.Cg-Rassf5tm1Kina J:168749 View
systemic lupus erythematosus Jak1M1Mhda/Jak1+ C3HeB/FeJ-Jak1M1Mhda J:199153 View
systemic lupus erythematosus Tg(Igh-V-CD40lg)#Tsub/0 C57BL/6-Tg(Igh-V-CD40lg)#Tsub J:128824 View
systemic lupus erythematosus Pdcd1tm1Hon/Pdcd1tm1Hon C.129S2(B6)-Pdcd1tm1Hon J:66979 View
systemic lupus erythematosus Ifih1Rgsc422/Ifih1Rgsc422 D2JJcl.B6JJcl-Ifih1Rgsc422 J:209917 View
systemic lupus erythematosus Ifih1Rgsc422/Ifih1+ D2JJcl.B6JJcl-Ifih1Rgsc422 J:209917 View
systemic lupus erythematosus Cdkn1atm1Led/Cdkn1atm1Led
Gadd45atm1Ajf/Gadd45atm1Ajf
either: (involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6) J:76041 View
systemic lupus erythematosus Gadd45atm1Ajf/Gadd45atm1Ajf either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129X1/SvJ * C57BL/6) J:76041 View
systemic lupus erythematosus Rc3h1san/Rc3h1san either: C57BL/6JSfdAnu-Rc3h1san/Anu or (involves: C57BL/6JSfdAnu * CBA/Ca) J:98938 View
systemic lupus erythematosus KitW-sh/KitW-sh
Lyntm1Ard/Lyntm1Ard
involves: 101 * 129P2/OlaHsd * C3H/HeH J:161523 View
systemic lupus erythematosus Rasgrp1lag/Rasgrp1lag involves: 129 * C57BL/6 J:85189 View
systemic lupus erythematosus Junbtm3Wag/Junbtm3Wag
Tg(KRT5-cre)1Tak/0
involves: 129/Sv * 129P2/OlaHsd * C3H * C57BL/6 J:155575 View
systemic lupus erythematosus Cd19tm1(cre)Cgn/Cd19+
Ep300tm2Reck/Ep300+
involves: 129/Sv * 129P2/OlaHsd * C57BL/6 J:147840 View
systemic lupus erythematosus Polbtm1.1Jbsw/Polbtm1.1Jbsw involves: 129/Sv * C57BL/6 J:206872 View
systemic lupus erythematosus C1qatm1Mjw/C1qatm1Mjw involves: 129P2/Ola * 129S/SvEv * C57BL/6 J:47315 View
systemic lupus erythematosus Lyntm1Ard/Lyntm1Ard involves: 129P2/OlaHsd J:161523 View
systemic lupus erythematosus Rxratm1Krc/Rxratm1Krc
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 J:168799 View
systemic lupus erythematosus Ppargtm1.1Gonz/Ppargtm1.1Gonz
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 J:168799 View
systemic lupus erythematosus Man2a1tm1Jxm/Man2a1tm1Jxm involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:74579 View
systemic lupus erythematosus Prdm1tm1Clme/Prdm1tm1Clme
Tg(Itgax-cre)1-1Reiz/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA J:178876 View
systemic lupus erythematosus Trove2tm1Woln/Trove2tm1Woln involves: 129S1/Sv * C57BL/6 J:84627 View
systemic lupus erythematosus Trove2tm1Woln/Trove2+ involves: 129S1/Sv * C57BL/6 J:84627 View
systemic lupus erythematosus Pdcd1tm1Hon/Pdcd1tm1Hon involves: 129S2/SvPas * C57BL/6 J:50688 View
systemic lupus erythematosus Ikzf3tm1Kge/Ikzf3tm1Kge involves: 129S4/SvJae * C57BL/6 J:50626, J:81805 View
systemic lupus erythematosus Mta2tm1.1Yzha/Mta2tm1.1Yzha involves: 129S4/SvJae * C57BL/6 * FVB/N J:137101 View
systemic lupus erythematosus C4btm1Crr/C4btm1Crr involves: 129S4/SvJae * C57BL/6J J:111811 View
systemic lupus erythematosus Def6Gt(OST307148)Lex/Def6Gt(OST307148)Lex involves: 129S5/SvEvBrd * C57BL/6 J:106469 View
systemic lupus erythematosus Cdkn1atm1Led/Cdkn1atm1Led involves: 129S6/SvEvTac J:76041 View
systemic lupus erythematosus Ptprctm1Weis/Ptprctm1Weis involves: 129X1/SvJ * C57BL/6 J:66501 View
systemic lupus erythematosus Ptprctm1Weis/Ptprc+ involves: 129X1/SvJ * C57BL/6 J:66501 View
systemic lupus erythematosus Tnfrsf13btm1Vmd/Tnfrsf13btm1Vmd involves: C57BL/6 J:82331 View
systemic lupus erythematosus Tg(Tlr7)1Boll/0 involves: C57BL/6 J:193610 View
systemic lupus erythematosus Ccr2tm1Blck/Ccr2tm1Blck
Faslpr/Faslpr
MRL.Cg-Ccr2tm1Blck Faslpr J:113343 View
systemic lupus erythematosus Faslpr/Faslpr
Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+
MRL.Cg-Faslpr Igh-Jtm2(3H9-VDJ*)Mwg J:131138 View
systemic lupus erythematosus Faslpr/Faslpr
Tlr9tm1Aki/Tlr9tm1Aki
MRL.Cg-Tlr9tm1Aki Faslpr J:113557 View
systemic lupus erythematosus Faslpr/Faslpr
Tnfrsf9tm1Byk/Tnfrsf9tm1Byk
MRL.Cg-Tnfrsf9tm1Byk Faslpr J:120559 View
systemic lupus erythematosus Faslpr/Faslpr MRL/Mp-Faslpr J:27634, J:28885, J:108760, J:131138 View
Transgenes and
Other Mutations
     hypersensitivity reaction type II disease Tg(Cd4-BCL2*G101A*D102A*D103A)AWnt/0 involves: C57BL/6 J:217939 View
Sjogren's syndrome Tg(Psp-Rbbp4)1Yoha/0 involves: C57BL/6 J:141378 View
systemic lupus erythematosus X/Yaa (NZB x BXSB)F1 J:6235 View
systemic lupus erythematosus X/Yaa (NZW x BXSB)F1 J:7276 View
systemic lupus erythematosus X/Yaa (NZW x SB)F1 J:7276 View
systemic lupus erythematosus Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+ B6.129P2-Igh-Jtm2(3H9-VDJ*)Mwg J:142389 View
systemic lupus erythematosus Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom
Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+
B6.129P2-Tcrbtm1Mom Igh-Jtm2(3H9-VDJ*)Mwg Tcrdtm1Mom J:142389 View
systemic lupus erythematosus Cd4tm1Mak/Cd4tm1Mak
Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+
B6.Cg-Cd4tm1Mak Igh-Jtm2(3H9-VDJ*)Mwg J:142389 View
systemic lupus erythematosus Tg(ACTB-TNFRSF6B)754Jwu/? B6.Cg-Tg(Actb-TNFRSF6B)754Jwu J:148162 View
systemic lupus erythematosus X/Yaa BXSB/MpJ J:6235, J:108760, J:7308 View
systemic lupus erythematosus X/Yaa BXSB/MpJScr J:10973 View
Additional Complex Models     autoimmune hemolytic anemia Tg(SV40-Igh-64C8)H3Hon/0
Tg(SV40-Igk4C8)L1Hon/0
involves: C57BL/6 J:139864 View
hypersensitivity reaction type II disease Axltm1Grl/Axltm1Grl
Mertktm1Grl/Mertktm1Grl
Tyro3tm1Grl/Tyro3tm1Grl
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J J:70420 View
Sjogren's syndrome Aec1NOD/Uf/Aec1NOD/Uf
Aec2NOD/Uf/Aec2NOD/Uf
B6.NOD-Aec2NOD/Uf Aec1NOD/Uf J:128900, J:129916, J:129282 View
systemic lupus erythematosus Csf2tm1Dran/Csf2tm1Dran
Il3tm1Glli/Il3tm1Glli
B6.129S2-Csf2tm1Dran Il3tm1Glli J:83086 View
systemic lupus erythematosus Ightm1(Igh564)Tik/Ightm1(Igh564)Tik
Igktm1(Igk564)Tik/Igktm1(Igk564)Tik
B6.129S4-Igktm1(Igk564)Tik Ightm1(Igh564)Tik J:113555 View
systemic lupus erythematosus Apoetm1Unc/Apoetm1Unc
Faslgld/Faslgld
B6.Cg-Faslgld Apoetm1Unc J:91058, J:200141 View
systemic lupus erythematosus Psen1tm1Bdes/Psen1+
Psen2tm1Bdes/Psen2tm1Bdes
involves: 129P2/OlaHsd J:91235 View
Disease phenotype
not observed
No similarity to the expected human disease phenotype was found.

        Allelic Composition Genetic Background Reference Phenotypes
NOT Models     systemic lupus erythematosus Tlr7tm1Flv/Y
X/Yaa
B6.Cg-Tlr7tm1Flv Yaa J:127600 View
systemic lupus erythematosus Csf2tm1Dran/Csf2tm1Dran
Ifngtm1Ts/Ifngtm1Ts
Il3tm1Glli/Il3tm1Glli
involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6 J:83086 View

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last database update
03/14/2017
MGI 6.08
The Jackson Laboratory