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Mouse Models of Amyotrophic Lateral Sclerosis 1; ALS1
Mouse Models All mouse models of Amyotrophic Lateral Sclerosis 1; ALS1 (OMIM ID: 105400)

        Allelic Composition Genetic Background Reference Phenotypes
      Sod2tm1Cje/Sod2tm1Cje involves: C57BL/6J J:45913 View
Mnx1tm4(cre)Tmj/Mnx1+
Tardbptm1.1Ckjs/Tardbptm1.2Cjks
involves: 129S1/Sv * C57BL/6J J:190254 View
Vegfatm2Pec/Vegfatm2Pec involves: 129S1/Sv * 129X1/SvJ J:69797 View
Vps54wr/Vps54wr involves: C57BL/6J * C57BL/Fa J:181019, J:196432 View
Transgenes and
Other Mutations
     Tg(Myl1-SOD1*G93A)#Amu/0 FVB/NJ-Tg(Myl1-SOD1*G93A)#Amu J:143747 View
Tg(NEFH)200Jpj/Tg(NEFH)200Jpj Not Specified J:69180 View
Tg(NEFH)200Jpj/0 Not Specified J:69180 View
Tg(NFH)120Jpj/Tg(NFH)120Jpj Not Specified J:69180 View
Tg(NFH)120Jpj/0 Not Specified J:69180 View
Tg(Prnp-SOD1*G37R,-PSEN1)110Dbo/Tg(Prnp-SOD1*G37R,-PSEN1)110Dbo involves: C3H * C57BL/6 J:104655 View
Tg(SOD1*)125Dbo/? involves: C3H/HeJ * C57BL/6J J:86421 View
Tg(SOD1*)DF7Yaw/Tg(SOD1*)DF7Yaw C57BL/6-Tg(SOD1*)DF7Yaw J:97932 View
Tg(SOD1*)DF7Yaw/0 C57BL/6-Tg(SOD1*)DF7Yaw J:97932 View
Isl1tm1(cre)Tmj/Isl1+
Tg(SOD1*G37R)1Dwc/0
involves: 129X1/SvJ * C57BL/6 J:109131 View
Tg(ITGAM-cre)2781Gkl/0
Tg(SOD1*G37R)1Dwc/0
involves: C57BL/6 * CBA J:109131 View
Tg(SOD1*G37R)9Dpr/0 involves: C3H/HeJ * C57BL/6J J:69178 View
Tg(SOD1*G37R)29Dpr/0 involves: C3H/HeJ * C57BL/6J J:69178, J:119631 View
Tg(SOD1*G37R)42Dpr/0 involves: C3H/HeJ * C57BL/6J J:69178 View
Tg(SOD1*G37R)106Dpr/0 involves: C3H/HeJ * C57BL/6J J:69178 View
Tg(SOD1*G85R)74Dwc/? Not Specified J:77600 View
Tg(SOD1*G85R)148Dwc/? Not Specified J:77600 View
Tg(SOD1*G85R)#Roos/0 involves: C57BL/6J J:147156 View
Tg(SOD1)2Gur/0
Tg(SOD1*G85R)#Roos/0
involves: C57BL/6 * C57BL/6J * SJL J:147156 View
Tg(Sod1*G86R)M1Jwg/0 involves: FVB/N J:22628, J:58733, J:91800 View
Tg(SOD1*G93A)1Gur/0 B6.Cg-Tg(SOD1*G93A)1Gur J:155140 View
Tg(SOD1*G93A)1Gur/0 B6SJL-Tg(SOD1*G93A)1Gur J:144199 View
Tg(SOD1*G93A)1Gur/0 B6SJL-Tg(SOD1*G93A)1Gur/J J:133155, J:143173, J:146652 View
Tg(SOD1)2Gur/0
Tg(SOD1*G93A)1Gur/0
involves: C57BL/6 * SJL J:109458 View
Tg(SOD1*G93A)1Gur/0 involves: C57BL/6 * SJL J:76718, J:91800, J:109458, J:130581 View
Tg(SOD1*G93A)2Gur/0 involves: C57BL/6 * SJL J:32665, J:78629, J:89928 View
Tg(SOD1*G93A)dl1Gur/0 involves: C57BL/6 * SJL J:106420 View
Cybbtm1Din/Y
Tg(SOD1*G93A)dl1Gur/0
B6.Cg-Cybbtm1Din Tg(SOD1*G93A)dl1Gur J:111782 View
Tg(SOD1*G127X)716Mrkl/Tg(SOD1*G127X)716Mrkl B6JBom.Cg-Tg(SOD1*G127X)716Mrkl J:175594 View
Tg(SOD1*H46R)#Maw/0 involves: C57BL/6 * DBA/2 J:99701 View
Tg(SOD1*H46R*H48Q)58Dbo/0 involves: C3H/HeJ * C57BL/6J J:119631 View
Tg(SOD1*H46R*H48Q)139Dbo/0 involves: C3H/HeJ * C57BL/6J J:119631 View
Tg(SOD1*L126Z)#Deng/0 involves: C57BL/6 * SJL J:109458 View
Tg(SOD1)2Gur/0
Tg(SOD1*L126Z)#Deng/0
involves: C57BL/6 * SJL J:109458 View
Tg(TARDBP)#Jpj/0 involves: C3H * C57BL/6 J:195184 View
Tg(TARDBP*A315T)#Jpj/0 involves: C3H * C57BL/6 J:195184 View
Tg(TARDBP*G348C)#Jpj/0 involves: C3H * C57BL/6 J:195184 View
Tg(Thy1-Sncg)HvP36Putt/? C57BL/6-Tg(Thy1-Sncg)HvP36Putt J:185793 View
Tg(Thy1-SOD1*G93A)T3Hgrd/Tg(Thy1-SOD1*G93A)T3Hgrd involves: C57BL/6 * CBA * FVB J:134095 View
Tg(Thy1-SOD1*G93A)T1Hgrd/0
Tg(Thy1-SOD1*G93A)T3Hgrd/0
involves: C57BL/6 * CBA * FVB J:134095 View
Tg(Thy1-TARDBP)4Singh/Tg(Thy1-TARDBP)4Singh involves: C57BL/6J * SJL/J J:157550 View
Tg(Thy1-TARDBP)4Singh/0 involves: C57BL/6J * SJL/J J:157550 View
Tg(Thy1-TARDBP)6Singh/Tg(Thy1-TARDBP)6Singh involves: C57BL/6 * C57BL/6J * SJL J:157550 View
Additional Complex Models     Tg(SOD1)2Gur/0
Tg(SOD1*A4V)A1073Gur/0
involves: C57BL/6 * SJL J:109458 View

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory