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All mouse models of hemolytic anemia with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | alpha thalassemia-X-linked intellectual disability syndrome |
Atrxtm1Rjg/Y Foxg1tm1(cre)Skm/Foxg1+ |
involves: 129P2/OlaHsd * C57BL/6 * FVB/N | J:95953 | View | |||
| alpha thalassemia-X-linked intellectual disability syndrome |
Atrxtm1Rjg/Y Tg(Nes-cre)2472Pick/0 |
involves: 129P2/OlaHsd * C57BL/6 * FVB/N | J:95953 | View | ||||
| alpha thalassemia-X-linked intellectual disability syndrome |
Atrxtm1Rjg/Y Tg(Pax6-cre,GFP)2Pgr/0 |
involves: 129P2/OlaHsd * C57BL/6 * FVB/N | J:145002 | View | ||||
| beta thalassemia |
Ahsptm1.1Mjwe/Ahsp+ Hbb-b1tm1Unc/Hbb-b1+ Hbb-b2tm1Unc/Hbb-b2+ |
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 | J:94421 | View | ||||
| beta thalassemia |
Ahsptm1.1Mjwe/Ahsptm1.1Mjwe Hbb-b1tm1Unc/Hbb-b1+ Hbb-b2tm1Unc/Hbb-b2+ |
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 | J:94421 | View | ||||
| beta thalassemia |
Ahsptm1Mjwe/Ahsp+ Hbb-b1tm1Unc/Hbb-b1+ Hbb-b2tm1Unc/Hbb-b2+ |
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 | J:94421 | View | ||||
| beta thalassemia |
Ahsptm1Mjwe/Ahsptm1Mjwe Hbb-b1tm1Unc/Hbb-b1+ Hbb-b2tm1Unc/Hbb-b2+ |
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 | J:94421 | View | ||||
| beta thalassemia |
Hbatm1(HBA)Tow/Hbatm1(HBA)Tow Hbbtm2(HBG1,HBD,HBB*)Ryan/Hbbtm2(HBG1,HBD,HBB*)Ryan |
Not Specified | J:148521 | View | ||||
| beta thalassemia |
Hbatm1(HBA)Tow/Hbatm1(HBA)Tow Hbbtm2(HBG1,HBD,HBB*)Ryan/Hbbtm3(HBG1,HBB)Tow |
Not Specified | J:148521 | View | ||||
| beta thalassemia | Hbb-b1MommeD7/Hbb-b1MommeD7 | involves: FVB/N | J:190446 | View | ||||
| beta thalassemia | Hbb-b1Rbc13/Hbb-b1Rbc13 | involves: BALB/c * C57BL/6 | J:190446 | View | ||||
| beta thalassemia |
Hbb-b1tm1Unc/Hbb-b1+ Hbb-b2tm1Unc/Hbb-b2+ |
B6;129-Hbb-b1tm1Unc Hbb-b2tm1Unc/J | J:211331 | View | ||||
| beta thalassemia |
Hbb-b1tm1Unc/Hbb-b1+ Hbb-b2tm1Unc/Hbb-b2+ |
involves: 129P2/OlaHsd | J:154187 | View | ||||
| beta thalassemia |
Hbb-b1tm1Unc/Hbb-b1+ Hbb-b2tm1Unc/Hbb-b2+ |
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 | J:94421 | View | ||||
| beta thalassemia |
Hbb-b1tm1Unc/Hbb-b1+ Hbb-b2tm1Unc/Hbb-b2+ |
involves: 129P2/OlaHsd * C57BL/6J | J:30155 | View | ||||
| beta thalassemia |
Hbb-b1tm1Unc/Hbb-b1+ Hbb-b2tm1Unc/Hbb-b2+ |
involves: 129P2/OlaHsd * C57BL/6N | J:185154 | View | ||||
| beta thalassemia |
Hbb-b1tm1Unc/Hbb-b1+ Hbb-b2tm1Unc/Hbb-b2+ Tg(HBB*)L2Pai/0 |
involves: 129P2/OlaHsd * C57BL/6 | J:97548 | View | ||||
| beta thalassemia | Hbbd3th/Hbbd3th | involves: C57BL/6 * DBA/2J | J:7209 | View | ||||
| beta thalassemia | Hbbtm1.1(HBG1,HBB*)Ryan/Hbb+ | involves: C57BL/6J | J:147906 | View | ||||
| beta thalassemia | Hbbtm2Unc/Hbb+ | involves: 129P2/OlaHsd * C57BL/6J | J:64295 | View | ||||
| congenital nonspherocytic hemolytic anemia | Gpi1b-m1Neu/Gpi1b-m1Neu | C3.Cg-Gpi1b-m1Neu | J:35956 | View | ||||
| congenital nonspherocytic hemolytic anemia | Gpi1b-m2Neu/Gpi1b-m2Neu | C3.Cg-Gpi1b-m2Neu | J:35956 | View | ||||
| hereditary spherocytosis type 1 | Ank1M1Wlst/Ank1M1Wlst | involves: 129S1/SvImJ * C3H/HeJ * C57BL/6 | J:170562 | View | ||||
| hereditary spherocytosis type 1 | Ank1nb/Ank1nb | either: (involves: non-inbred stock) or (involves: C57BL/6) or (involves: WB/Re) | J:11441 | View | ||||
| hereditary spherocytosis type 1 | Ank1pale/Ank1pale | C57BL/6J-Ank1pale/GrsrJ | J:222308 | View | ||||
| hereditary spherocytosis type 1 | Ank1Rbc2/Ank1Rbc2 | involves: 129S1/Sv * BALB/c | J:148127 | View | ||||
| hereditary spherocytosis type 3 | Spta1ihj/Spta1ihj | involves: HRS/J * LAH | J:157766 | View | ||||
| hereditary spherocytosis type 3 | Spta1sph-2Bc/Spta1sph-2Bc | involves: SELH | J:7048, J:7501 | View | ||||
| hereditary spherocytosis type 3 | Spta1sph-ha/Spta1sph-ha | involves: DBA/1J | J:14946, J:30699 | View | ||||
| hereditary spherocytosis type 3 | Spta1sph/Spta1sph | either: (B6.C3-Spta1sph x WB.C3-Spta1sph)F1 or (WB.C3-Spta1sph x B6.C3-Spta1sph)F1 | J:6695 | View | ||||
| hereditary spherocytosis type 3 | Spta1sph/Spta1sph | involves: C3H | J:12276 | View | ||||
| pyruvate kinase deficiency of red cells | Pklrchar4/Pklrchar4 | involves: A/J * C57BL/6 | J:86735 | View | ||||
| pyruvate kinase deficiency of red cells | Pklrslc/Pklrslc | CBA/NSlc-Pklrslc | J:29199 | View | ||||
| | autoimmune hemolytic anemia |
Tg(KRT5-rtTA)1Glk/0 Tg(tetO/CMV-Tslp)#Sfz/0 |
C.Cg-Tg(KRT5-rtTA)1Glk Tg(tetO/CMV-Tslp)#Sfz | J:182756 | View | |||
| beta thalassemia | Klf1tm1Sho/Klf1tm1Sho | involves: 129S4/SvJae * C57BL/6 | J:25651 | View | ||||
| congenital dyserythropoietic anemia |
Diaph3tm1.1Pji/Diaph3tm1.1Pji Tg(Mx1-cre)1Cgn/0 |
involves: C57BL/6J * CBA/J | J:293763 | View | ||||
| congenital dyserythropoietic anemia | Man2a1tm1Jxm/Man2a1tm1Jxm | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:41621 | View | ||||
| hereditary spherocytosis | Klf1Nan/Klf1+ | either: B6.Cg-Klf1Nan or WB.Cg-Klf1Nan | J:162530 | View | ||||
| hereditary spherocytosis type 1 | Add2tm1Llp/Add2tm1Llp | involves: 129S4/SvJae * C57BL/6J | J:71029 | View | ||||
| hereditary spherocytosis type 1 | Epb42tm1Llp/Epb42tm1Llp | involves: 129P2/OlaHsd * C57BL/6J | J:67412 | View | ||||
| hereditary spherocytosis type 1 | Spta1sph-2Bc/Spta1sph-2Bc | involves: SELH | J:7048, J:7501 | View | ||||
| hereditary spherocytosis type 1 | Spta1sph-ha/Spta1sph-ha | involves: DBA/1J | J:14946, J:30699 | View | ||||
| hereditary spherocytosis type 1 | Spta1sph/Spta1sph | involves: C3H | J:12276 | View | ||||
| hereditary spherocytosis type 4 | Slc4a1wan/Slc4a1wan | C3H/HeJ-Slc4a1wan/J | J:89043 | View | ||||
| thalassemia | Ppp1r15atm1.1Ajf/Ppp1r15atm1.1Ajf | involves: 129 * C57BL/6 | J:106905 | View | ||||
| | alpha thalassemia | Hbab2(th)/Hba+ | either: (involves: 101 * SEC) or (involves: 101 * C57BL * SEC) | J:123943 | View | |||
| alpha thalassemia | Hbab2(th)/Hba+ | involves: C57BL/6J * SEC | J:32654 | View | ||||
| alpha thalassemia | Hbab2(th)/Hba+ | SEC-Hbab2(th) | J:6452 | View | ||||
| alpha thalassemia | Hbab3(th)/Hba+ | either: (involves: 101 * SEC) or (involves: 101 * C57BL * SEC) | J:123943 | View | ||||
| alpha thalassemia | Hbab3(th)/Hba+ | involves: C57BL/6J * SEC | J:32654 | View | ||||
| alpha thalassemia | Hbab3(th)/Hba+ | SEC-Hbab3(th) | J:6452 | View | ||||
| alpha thalassemia | Hbath-J/Hba+ | involves: C57BL/6J | J:45721, J:32654 | View | ||||
| Transgenes and Other Mutations | alpha thalassemia | Hbatm1Ney/Hbatm1Ney | either: (involves: 129P2/OlaHsd) or (involves: 129X1/SvJ) | J:86682 | View | |||
| beta thalassemia | Hbbtm1Unc/Hbbtm1Unc | involves: 129P2/OlaHsd * C57BL/6J | J:4932 | View | ||||
| beta thalassemia | Rr320tm1.1Mkg/Rr320+ | involves: 129 | J:60714 | View | ||||
| beta thalassemia | Rr320tm2Mkg/Rr320tm2Mkg | involves: 129S4/SvJaeSor | J:28981 | View | ||||
| Additional Complex Models | autoimmune hemolytic anemia |
Tg(SV40-Igh-64C8)H3Hon/0 Tg(SV40-Igk4C8)L1Hon/0 |
involves: C57BL/6 | J:139864 | View | |||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | beta thalassemia | Del(7Or2h1-Rr320)1Mkg/+ | involves: 129 | J:139198 | View | |||
| congenital dyserythropoietic anemia type III | Kif23tm1.1Igo/Kif23+ | involves: C57BL/6 * C57BL/6NTac | J:321429 | View | ||||
| congenital dyserythropoietic anemia type III | Kif23tm1.1Igo/Kif23tm1.1Igo | involves: C57BL/6 * C57BL/6NTac | J:321429 | View | ||||
| Rh deficiency syndrome | Rhagtm1Goo/Rhagtm1Goo | involves: 129P2/OlaHsd * C57BL/6 | J:182122 | View | ||||
| Rh deficiency syndrome |
Rhagtm1Goo/Rhagtm1Goo Rhdtm1Goo/Rhdtm1Goo |
involves: 129P2/OlaHsd * C57BL/6 | J:182122 | View | ||||