Excel File Text File All mouse models of demyelinating disease with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      multiple sclerosis Prf1tm1Sdz/Prf1tm1Sdz C57BL/6-Prf1tm1Sdz/J J:120427 View
multiple sclerosis Tg(Gfap-TNF*)K21Gkl/0
Tnfrsf1atm1Blt/Tnfrsf1a+
involves: 129P2/OlaHsd * C57BL/6 * CBA J:106592 View
multiple sclerosis Tg(Tnf)6074Gkl/0
Tnfrsf1btm1Mwm/Tnfrsf1btm1Mwm
involves: 129S2/SvPas * C57BL/6 * CBA J:106592 View
multiple sclerosis Tg(Tnf)6074Gkl/0 involves: C57BL/6 * CBA J:106592 View
multiple sclerosis Tg(Gfap-TNF*)K21Gkl/0 involves: C57BL/6 * CBA J:106592 View
multiple sclerosis Lrch1em1Hwa/Lrch1em1Hwa Not Specified J:238772 View
Transgenes and
Other Mutations
     multiple sclerosis Tg(Mbp-Pad2)28Fgm/0 involves: CD-1 J:142650 View
multiple sclerosis Tg(Mbp-Pad2)28Fgm/Tg(Mbp-Pad2)28Fgm involves: CD-1 J:142650 View
multiple sclerosis Tg(PLP1*)4Rsj/0 involves: CD-1 J:161344, J:171534 View
multiple sclerosis Tg(H2-Kb-Tcra,-Tcrb)1640Kurs/0 SJL.FVB-Tg(H2-Kb-Tcra,-Tcrb)1640Kurs J:149511 View
Additional
Complex
Models
     multiple sclerosis Mogtm1(cre)Gkl/Mogtm1(cre)Gkl
Tg(Tcra2D2,Tcrb2D2)1Kuch/0
C57BL/6-Mogtm1(cre)Gkl Tg(Tcra2D2,Tcrb2D2)1Kuch J:151335 View
multiple sclerosis H2u/H2u
Rag1tm1Mom/Rag1tm1Mom
Tg(Tcra19,Tcrb19)#Stl/0
either: (involves: 129S7/SvEvBrd * C57BL/6 * PL/J) or (involves: 129S7/SvEvBrd * C57BL/6 * C57BL/10 * PL/J) J:19795 View
multiple sclerosis Igh-Jtm1Aigl/Igh-J+
Mogtm1Dpd/Mogtm1Dpd
Tg(Tcra2D2,Tcrb2D2)1Kuch/0
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 J:151335 View
multiple sclerosis Igh-Jtm1Aigl/Igh-J+
Tg(Tcra2D2,Tcrb2D2)1Kuch/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:151335 View
multiple sclerosis H2dlAb1-Ea/H2dlAb1-Ea
Tg(HLA-DRA,HLA-DRB5*0101)hiKito/0
Tg(TRATL3A6,TRBTL3A6)#Kito/0
involves: 129S2/SvPas * C57BL/6 J:189816 View
multiple sclerosis Mogtm1Dpd/Mogtm1Dpd
Rag2tm1Cgn/Rag2tm1Cgn
Tg(Tcra2D2,Tcrb2D2)1Kuch/0
involves: 129S2/SvPas * C57BL/6 J:151335 View
multiple sclerosis Mogtm1Dpd/Mogtm1Dpd
Tg(Tcra2D2,Tcrb2D2)1Kuch/0
involves: 129S2/SvPas * C57BL/6 J:151335 View
multiple sclerosis Gt(ROSA)26Sortm1(DTA)Jpmb/Gt(ROSA)26Sor+
Tg(Plp1-cre/ERT)3Pop/0
involves: 129S/SvEv * C57BL/6 * DBA/2 J:234435 View
multiple sclerosis H2u/H2u
Tg(TCRA)B1Jg/?
Tg(TCRB)C14Jg/?
involves: C57BL/6 * C57BL/10SnSg * DBA/2 * PL/J J:92991 View
multiple sclerosis Rag2tm1.1Cgn/Rag2tm1.1Cgn
Tg(HLA-DR2)#Lfug/0
Tg(TCROb.1A12)#Lfug/0
involves: C57BL/6 * DBA/2 J:134764 View
multiple sclerosis Tg(HLA-DR2)#Lfug/0
Tg(TCROb.1A12)#Lfug/0
involves: C57BL/6 * DBA/2 J:134764 View
multiple sclerosis Tg(Cd4-CD4)2362Litt/0
Tg(HLA-DR2)#Lfug/0
Tg(TCROb.1A12)#Lfug/0
involves: C57BL/6 * DBA/2 * SJL J:134764 View