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All mouse models of orofacial cleft with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | cleft lip |
Irf6tm1Bcsl/Irf6tm1Bcsl Pitx2tm4(cre)Jfm/Pitx2+ |
involves: 129 | J:275989 | View | |||
| X-linked cleft palate with or without ankyloglossia | Tbx22tm1.1Sta/Tbx22tm1.1Sta | involves: 129 * CD-1 | J:153100 | View | ||||
| X-linked cleft palate with or without ankyloglossia | Tbx22tm1.1Sta/Y | involves: 129/Sv * CD-1 | J:153100 | View | ||||
| | cleft palate | b2b1470Clo/b2b1470Clo | C57BL/6J-b2b1470Clo | J:175213 | View | |||
| cleft palate | b2b1594Clo/b2b1594Clo | C57BL/6J-b2b1594Clo | J:175213 | View | ||||
| cleft palate |
Cdc42tm1.1Ayam/Cdc42tm1.1Ayam Tg(Mpz-cre)94Imeg/0 |
Not Specified | J:250065 | View | ||||
| cleft palate | Golgb1em8Lanyu/Golgb1em8Lanyu | FVB/NJ-Golgb1em8Lanyu | J:235669 | View | ||||
| cleft palate | Golgb1em8Lanyu/Golgb1em33Lanyu | FVB/NJ-Golgb1em8Lanyu | J:235669 | View | ||||
| cleft palate | Golgb1em33Lanyu/Golgb1em33Lanyu | FVB/NJ-Golgb1em8Lanyu | J:235669 | View | ||||
| cleft palate | Golgb1em33Lanyu/Golgb1m1Lanyu | involves: A/J * FVB/NJ | J:235669 | View | ||||
| cleft palate | Golgb1m1Lanyu/Golgb1m1Lanyu | A/J-Golgb1m1Lanyu | J:235669 | View | ||||
| cleft palate |
Prmt1tm1Rchd/Prmt1tm1Rchd H2az2Tg(Wnt1-cre)11Rth/H2az2+ |
involves: 129/Sv * C57BL/6J * CBA/J | J:289243 | View | ||||
| cleft palate | Six2tm3(EGFP/cre/ERT2)Amc/Six2tm3(EGFP/cre/ERT2)Amc | involves: 129/Sv * C57BL/6J | J:285711 | View | ||||
| cleft palate | Specc1lem3Kumc/Specc1l+ | involves: C57BL/6J * FVB/NJ | J:324294 | View | ||||
| cleft palate | Specc1lem4Kumc/Specc1l+ | involves: C57BL/6J * FVB/NJ | J:324294 | View | ||||
| cleft soft palate |
Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm Tg(KRT14-cre)52Smr/0 |
involves: 129S6/SvEvTac * C57BL/6J * SJL/J | J:208431 | View | ||||
| isolated cleft palate | Satb2tm1(cre)Vit/Satb2+ | involves: C57BL/6 | J:116770 | View | ||||
| orofacial cleft | Msx1tm1Rilm/Msx1tm1Rilm | either: (involves: 129S4/SvJae-Msx1tm1Rilm) or (involves: 129S4/SvJae * BALB/c) or (involves: 129X1/SvJae * C57BL/6J) | J:17489 | View | ||||
| orofacial cleft | Tfap2atm1Will/Tfap2atm2.1Will | involves: 129S1/Sv * Black Swiss | J:217408 | View | ||||
| Transgenes and Other Mutations | cleft palate |
Tg(CAG-LacZ,-ACVR1*,-EGFP)35-1Mis/0 Tg(KRT14-cre)1Amc/0 |
involves: C57BL/6 * CBA * DBA/2 | J:233662 | View | |||