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Human Disease and Mouse Model Detail
Human Disease Frontotemporal Lobar Degeneration with Tdp43 Inclusions, Grn-Related
OMIM ID: 607485
Synonyms Frontotemporal Dementia with Tdp43 Inclusions, Grn-Related; Frontotemporal Dementia, Ubiquitin-Positive; FTDU; Frontotemporal Lobar Degeneration with Ubiquitin-Positive Inclusions; FTLDU; Ftld-Tdp, Grn-Related
View all models View ALL (6) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Gene is associated with the disease in this species
      Mouse Homologs Human Homologs Mouse Models Mouse : Human
Homology Class
     Grn GRN*   1:1 Homology
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  Tg(Camk2a-Tardbp)#Ckjs View 1 model
  Tg(Prnp-TARDBP)3cPtrc View 1 model
  Tg(TARDBP)#Jpj View 1 model
  Tg(TARDBP*A315T)#Jpj View 1 model
  Tg(TARDBP*G348C)#Jpj View 1 model
  Tg(Thy1-TARDBP*)BOddo View 1 model
References Disease References using Mouse Models (5)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory