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Human Disease and Mouse Model Detail
Human Disease Pulmonary Disease, Chronic Obstructive; COPD
OMIM ID: 606963
Human Phenotype Ontology associations
View all models View ALL (7) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Disease is associated/modeled with this Gene or a homolog. More...
      Human Homologs Mouse Homologs Mouse Models Homology Source
     IL18 Il18* View 1 model HomoloGene and HGNC
JUN Jun* View 1 model HomoloGene
LTBP4 Ltbp4* View 1 model HomoloGene and HGNC
SCNN1B Scnn1b* View 1 model HomoloGene
TNF Tnf* View 1 model HomoloGene
WWTR1 Wwtr1* View 1 model HomoloGene
     HMOX1* Hmox1   HomoloGene
MMP1* Mmp1a, Mmp1b   HGNC
SERPINA1* Serpina1a, Serpina1b, Serpina1c, Serpina1d, Serpina1e   HomoloGene
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  Tg(Scgb1a1-Scnn1b)6608Bouc View 1 model
  Tg(SFTPC-Il18)AThos View 1 model
  Tg(SFTPC-Tnf)2Pva View 1 model
  Tg(tetO-IL1B)KBry View 1 model
References Disease References using Mouse Models (10)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.05
The Jackson Laboratory