| Human Disease |
Cerebral Amyloid Angiopathy, App-Related OMIM ID: 605714 |
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| Synonyms | Amyloidosis, Cerebroarterial, App-Related; Amyloidosis, Hereditary, with Cerebral Hemorrhage, Dutch Variant; HCHWAD; Cerebral Amyloid Angiopathy, App-Related, Arctic Variant; Cerebral Amyloid Angiopathy, App-Related, Dutch Variant; Cerebral Amyloid Angiopathy, App-Related, Flemish Variant; Cerebral Amyloid Angiopathy, App-Related, Iowa Variant; Cerebral Amyloid Angiopathy, App-Related, Italian Variant | ||||||||||||||||||||||||||||
| View all models | View ALL (8) mouse models for this human disease. | ||||||||||||||||||||||||||||
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Genes and mouse models |
Mutations in human and/or mouse homologs are associated with this disease
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Transgenes and other genome features |
Transgenes and other genome features developed in mice to model this disease.
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| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Lrp1tm2Her/Lrp1tm2Her Tg(APP695)3Dbo/0 Tg(PSEN1)5Dbo/0 Tg(Tagln-cre)1Her/0 |
involves: 129S7/SvEvBrd * C3H/HeJ * C57BL/6 * C57BL/6J * SJL | J:192453 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Lrp1tm2Her/Lrp1tm2Her Tg(APP695)3Dbo/0 Tg(PSEN1)5Dbo/0 Tg(Tagln-cre)1Her/0 |
involves: 129S7/SvEvBrd * C3H/HeJ * C57BL/6 * C57BL/6J * SJL | J:192453 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Lrp1tm2Her/Lrp1tm2Her Tg(APP695)3Dbo/0 Tg(PSEN1)5Dbo/0 Tg(Tagln-cre)1Her/0 |
involves: 129S7/SvEvBrd * C3H/HeJ * C57BL/6 * C57BL/6J * SJL | J:192453 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(Thy1-APP)3Somm/0 |
involves: C57BL/6J * DBA/2 | J:67583 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(Thy1-AppDutch)#Jckr/0 |
involves: C57BL/6J | J:92796, J:162531 | View |
| Tg(Thy1-AppDutch)#Jckr/0 Tg(Thy1-BACE1)54/4Ppa/0 |
involves: C57BL/6 | J:162531 | View |
| Tg(Thy1-AppDutch)#Jckr/0 Tg(Thy1-PSEN1*G384A)45Jckr/0 |
involves: C57BL/6 * C57BL/6J * DBA/2 | J:92796 | View |
| Abcc1tm1Bor/Abcc1tm1Bor Tg(Thy1-AppDutch)#Jckr/0 |
FVB.Cg-Abcc1tm1Bor Tg(Thy1-AppDutch)#Jckr | J:178230 | View |
| Allelic Composition | Genetic Background | Reference | Phenotypes |
| Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz/0 |
C57BL/6-Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz | J:165986 | View |
| Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz/0 Tg(Thy1-MAPT)183Gotz/0 |
B6.Cg-Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz Tg(Thy1-MAPT)183Gotz | J:154968 | View |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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