Human Disease and Mouse Model Detail

Human Disease

Craniosynostosis, Type 2; CRS2
OMIM ID: 604757

Synonyms

Craniosynostosis, Boston-Type; CSB

View all models

View ALL (4) mouse models for this human disease.

Genes and
mouse models

Mutations in human and/or mouse homologs are associated with this disease

*Gene is associated with the disease in this species
Mouse Homologs	Human Homologs	Mouse Models	Mouse : Human Homology Class
Msx2*	MSX2*	View 1 model	1:1 Homology

Transgenes and
other genome features

Transgenes and other genome features developed in mice to model this disease.

	Transgenes and Other Genome Features	Mouse Models
	Tg(CMV-Msx2*P7H)1Rem	View 1 model
	Tg(Msx2)1Rem	View 1 model
	Tg(Timp1-Msx2*P7H)1Rem	View 1 model

Allelic Composition	Genetic Background	Reference	Phenotypes
Msx2tm1Rilm/Msx2tm1Rilm	either: (involves: 129S4/SvJae-Msx2tm1Rilm) or (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6J)	J:61509	View

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(CMV-Msx2*P7H)1Rem/0	involves: C57BL/6 * CBA/J	J:26513	View

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Msx2)1Rem/0	involves: C57BL/6 * CBA/J	J:26513	View

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Timp1-Msx2*P7H)1Rem/0	involves: C57BL/6 * CBA/J	J:26513	View

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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